Corning Incorporated

Paul Michael Szlosek

Gregory Roger Martin

Allison Jean Tanner

Paul Ernest Gagnon, Jr

Scott Matthew Bennett

Gregory Mathus

William Joseph Lacey

Michael Kurt Schaefer

Brian Robb Douglass

Kevin Thomas Morris

James B Stamatoff

Paul W Maxim

John Wilfred Coddaire

A spheroid cell culture article including:

Spheroid cell culture article and methods thereof

Spheroid cell culture well article and methods thereof

A multiwell plate is described that is used for assaying samples and is made from a plastic upper plate which forms the sidewalls of one or more wells and a transparent lower plate which forms the bottom walls of the wells. The upper plate and lower plate are attached and bound to one another by a series of rings. Also described herein is a method for making such multiwell plates.

Multiwell plate having transparent well bottoms and method for making the mulitiwell plate

Packages and methods for containing slides adapted for the attachment of biomolecules. The containers do not degrade the ability of biomolecules to attach to the surface when the slides are stored or shipped in the container.

Substrate container that does not degrade substrate surface

Microplates and methods for manufacturing microplates. The microplate is designed to allow UV radiation to pass through the bottom wells of the microplate so that the microplate can be used for assaying samples by use of UV absorbance. In one embodiment, the microplate comprises at least first and second wells, each well having a UV permeable bottom. In another embodiment, the microplate comprises a frame having an upper portion and a lower portion contiguous with the upper portion and a sheet disposed between the upper portion and the lower portion and defining the bottom of at least one well of the microplate. One embodiment of the method includes steps of inserting a sheet of UV permeable material into a mold cavity that includes sections shaped to form the sidewalls of the plurality of wells, injecting molten plastic material into the mold cavity, and cooling the plastic material to form the microplate with the plastic material forming the sidewalls of each of the first and second wells and the sheet of UV permeable material forming the bottom of each of the first and second wells. Another embodiment of the method includes providing an upper plate defining sidewalls of at least one well, adhering an intermediate layer to the upper plate and adhering a sheet of UV permeable material to the intermediate layer. A further embodiment of the method includes inserting a sheet of material having at least one hole into a mold cavity, injecting a molten plastic material into the mold cavity and cooling the plastic material to form a microplate.

Method of making microplates with UV permeable bottom wells

A microplate and a method for manufacturing microplates. The microplate is designed to reduce optical cross-talk during the assaying of samples. The microplate includes a plurality of wells having light permeable sidewalls, a layer of light permeable material forming a bottom of the wells, and ribs of light impermeable material extending through the layer of light permeable material. The method includes steps of inserting a plate of light permeable material into a mold cavity that includes sections shaped to form the sidewalls of the plurality of wells, injecting molten light impermeable material into the mold cavity, and cooling the light impermeable material to form the microplate with the light impermeable material forming the sidewalls of each of the plurality of wells and the plate of light permeable material forming the bottom wall of each of the plurality of wells.

Microplates which prevent optical cross-talk between wells

Microplates with UV permeable bottom wells

A microplate and a method for manufacturing microplates. The microplate is designed to reduce optical cross-talk during the assaying of samples. The microplate comprises a plurality of wells having light permeable sidewalls, a layer of light permeable material forming a bottom of the wells, and ribs of light impermeable material extending through the layer of light permeable material. The method includes steps of inserting a plate of light permeable material into a mold cavity that includes sections shaped to form the sidewalls of the plurality of wells, injecting molten light impermeable material into the mold cavity, and cooling the light impermeable material to form the microplate with the light impermeable material forming the sidewalls of each of the plurality of wells and the plate of light permeable material forming the bottom wall of each of the plurality of wells.

Growing community of inventors

Kennebunk, ME, United States of America

Paul Michael Szlosek