The University of North Carolina at Chapel Hill

Cell Microsystems, Inc.

Paul Michael Armistead

Nancy L Allbritton

Steven C Gebhart

Nicholas C Trotta

Peter Joseph Attayek

Robert W McClellan

Robert W Mcclellan

Embodiments of the disclosed subject matter provide an automated method and system to isolate and collect cells using computerized analysis of images of cells and their surroundings obtained from a digital imaging device or system. Embodiments of the disclosed subject matter make use of a 'microwell array,' which can comprise a formed, elastomeric grid of indentations or “wells.” Many, most, or all of the wells in a microwell array can contain a releasable, microfabricated element, which can be referred to as a “raft.” Embodiments of the disclosed subject matter provide a system and method for cell collection that includes computerized identification and collection of rafts with isolated single cells or a specific group or groups of cells, eliminating the need for continuous human identification and selection.

Automated collection of a specified number of cells

Growing community of inventors

Durham, NC, United States of America

Paul Michael Armistead