Seahorse Bioscience

Agilent Technologies, Inc.

Seahorse Biosciences

Paul McGarr

Jay S Teich

Jason Dell'Arciprete

Suzanne Armitstead

Sarah Burroughs

Andy C Neilson

Andrew C Neilson

The present disclosure relates to methods and apparatus for measuring of multiple physiological properties of biological samples, such as measuring biological flux.

Method and apparatus for measuring physiological properties of biological samples

A multiwell microplate for holding liquid samples, and a method of use thereof. The multiwell microplate includes a frame defining a plurality of wells disposed in a single column, each well having an opening with a length l. A moat is disposed about the plurality of wells. A plurality of walls traverses the moat, the walls defining a plurality of compartments, each compartment having a length lselected from a range of greater than land less than 6l. A multiwell microplate carrier includes a body defining a plurality of regions configured to hold a plurality of multiwell microplates in parallel, each multiwell microplate defining a single column of wells, and each of the regions defining a plurality of openings that are adapted to mate with the single columns of wells.

Single column microplate system and carrier for analysis of biological samples

An apparatus including a plurality of wells for conducting analysis of three-dimensional cell samples (e.g., tissue samples) and methods for experimenting with a three-dimensional sample. A removable insert for use with the apparatus enables plunger-driven perfusion of the three-dimensional sample.

Apparatus and methods for three-dimensional tissue measurements based on controlled media flow

Cartridge

Microplate assembly

Carrier

Microplate

Growing community of inventors

Longmeadow, MA, United States of America

Paul McGarr