Praecis Pharmaceuticals, Inc.

Interleukin Genetics, Inc.

Paul M Martha, Jr

Gordon W Duff

Marc B Garnick

Christopher J Molineaux

Simon Van Dijk

Alex DePaoli

Methods for treating FSH related conditions, such as prostatic intraepithelial neoplasia, pedophilia, infertility, or vaginal bleeding, with GnRH antagonists are disclosed. The methods of the invention generally feature administering to a subject a GnRH antagonist suitable for in vivo administration and able to reduce both plasma FSH and LH levels in a subject, in an amount or in a formulation effective to reduce plasma FSH levels in the subject to a symptom alleviating level. In vitro fertilization and male contraceptive methods are also provided.

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Topsfield, MA, United States of America

Paul M Martha, Jr