Gen-Probe, Inc.

Paul M Darby

Damon Kittredge Getman

Jo Ann Jackson

Jeffrey M Linnen

Reinhold B Pollner

Wen Wu

Siobhan Miick

Geoffrey G Dennis

Sylvia Ann Norman

Ankur Shah

Barbara Lynn Eaton

Elizabeth M Marlowe

Siobhán M Miick

Amber Hillius

Matthias Jost

Patrick Lynn Peterson

Jimmykim Pham

JoAnn Jackson

Matthew Brentnall

Ankur H Shah

Hee Cheol Kim

Sheila M J Aubin

Joshua Kalani Moberly

Meghan A O'donnell

Siobhan M Miick

Jeffery Linnen

Joann Jackson

Sheila MJ Aubin

Jeffery M Linnen

Oligomer nucleotides, compositions, methods, kits, and uses are provided for detecting or quantifying a Human Cytomegalovirus virus 1 (CMV (human herpesvirus 5, HHV5) nucleic acid, e.g., using nucleic acid amplification and hybridization assays. Multiphase amplification of a CMV target sequence is also described. The oligomer nucleotides, compositions, methods, kits, and uses can be used to amplify and/or detect the UL56 gene of CMV.

Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus

This disclosure provides oligomers, combinations of oligomers, compositions, kits, uses, and methods for detecting a C1orf43 nucleic acid, such as C1orf43 mRNA, such as human C1orf43 mRNA, in a sample.

Compositions and methods for detecting C1orf43 nucleic acid

Provided herein are compositions, kits, and methods for detecting methicillin-resistant(MRSA) nucleic acids. In some embodiments, the compositions, kits, and methods can be used to detect one or more of type i, ii, iii, iv, v, vi, vii, viii, ix, xii, xiii, xiv, xv, or xxi SCCmec right extremity junction (MREJ) MRSA nucleic acids and one or more of mecA, mecC, and/or an additional-specific gene.

Compositions and methods for detecting

This disclosure provides oligomers, compositions, and kits for detecting and quantifying Hepatitis C virus (HCV), including different genotypes and variants thereof, and related methods and uses. In some embodiments, oligomers target the 5' untranslated region of HCV and are configured to provide substantially equivalent quantification of different genotypes and variants of HCV.

Compositions and methods for detecting or quantifying hepatitis C virus

Disclosed are nucleic acid oligomers, including amplification oligomers, capture probes, and detection probes, for detection of a 16S rRNA or its encoding gene from bacterial species associated with bacterial vaginosis. Also disclosed are methods of specific nucleic acid amplification and detection using the disclosed oligomers, as well as corresponding reaction mixtures and kits.

Compositions and methods for detecting BV-associated bacterial nucleic acid

Methods for detecting influenza virus A and influenza virus B nucleic acids in biological samples by using in vitro amplification and detection are disclosed. Compositions that are target-specific nucleic acid sequences and kits comprising target-specific nucleic acid oligomers for amplifying in vitro influenza virus A or influenza virus B nucleic acid and detecting amplified nucleic acid sequences are disclosed.

Compositions and assays to detect influenza virus A and B nucleic acids

Compositions, methods and kits for detecting Group A streptococci. Particularly described are oligonucleotides that are useful as amplification primers and hybridization probes for detecting very low levels of Group A streptococci nucleic acids.

Compositions for detecting group A streptococci

Growing community of inventors

San Diego, CA, United States of America

Paul M Darby