Cardiovalve Ltd.

Paul Kaye

Ilia Hariton

Tal Reich

Michael Albitov

Boaz Harari

Maxim Karalnik

During a medical procedure, a transseptal fenestration is made at a septum of the heart and a shunt is implanted into the transseptal fenestration. During the same medical procedure, a transapical puncture is made into a left ventricle of the heart. A prosthetic valve is delivered via the transapical puncture and implanted at a mitral valve of the heart. Subsequently to delivering the prosthetic valve and making the transseptal fenestration, the transapical puncture is closed. Other embodiments are also described.

Techniques for providing a replacement valve and transseptal communication

A method is provided, including (1) identifying the subject as having mitral valve regurgitation; (2) during a medical procedure, in response to identifying the subject as having mitral valve regurgitation, implanting a prosthetic valve at a mitral valve site of the heart; and (3) during the same medical procedure, implanting a therapeutic septal device at a septum of the heart. Other embodiments are also described.

A tool () for use with an implant () includes a housing () and a controller (). The housing includes a tubular wall () that circumscribes a longitudinal axis; is dimensioned to house at least part of the implant; and defines a track () that follows a generally-helical path around the longitudinal axis. The controller includes a rod () that extends from a proximal part of the tool to the housing; and an actuator (). The actuator is fixedly coupled to the rod, includes an engaging element () that engages the track, and is rotatable with respect to the housing. The controller and the housing mechanically cooperate such that rotation of the actuator with respect to the housing slides the housing longitudinally with respect to the actuator. Other embodiments are also described.

Minimally-invasive delivery systems

A method is provided, comprising: (1) making a transapical puncture into a left ventricle of the heart; (2) making a transseptal fenestration in the heart; (3) delivering a prosthetic valve via the transapical puncture and implanting the prosthetic valve at a mitral valve of the heart; and (4) subsequently to delivering the prosthetic valve and making the transseptal fenestration, closing the transapical puncture. Other embodiments are also described.

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Modiin, Israel

Paul Kaye