Case Western Reserve University

Paul Hunter Peckham

Brian N Smith

Geoffrey Bart Thrope

James Robert Buckett

Jorge Ernesto Letechipia

Kevin L Kilgore

Timothy J Crish

Christa Wheeler Moss

William D Memberg

Christa Wheeler

Michael W Keith

Multiple designs, systems, methods and processes for control using electrical signals recorded from clinically paralyzed muscles and nerves are presented. The discomplete neural prosthesis system and method for clinically paralyzed humans utilizes a controller. The controller is adapted to receive a volitional electrical signal generated by the human that is manifest below the lesion that causes the clinical paralysis. The controller uses at least the volitional electrical signal to generate a control signal that is output back to a plant to change the state of the plant, which in one aspect is one or more of the user's paralyzed muscles to achieve a functional result or to devices in the environment around the user that are adapted to receive commands from the controller.

Neural prosthesis system and method of control

A neural prosthesis includes a centralized device that can provide power, data, and clock signals to one or more individual neural prosthesis subsystems. Each subsystem may include a number of individually addressable, programmable modules that can be dynamically allocated or shared among neural prosthetic networks to achieve complex, coordinated functions or to operate in autonomous groups.

Neural prosthesis

Implantable networked neural system

An input command controller (A) provides logic function selection signals and proportional signals. The signals are generated by movement of a ball member ( ) and socket member ( ) relative to two orthogonal axes. When the joystick is implanted, a transmitter ( ) transmits the signals to a patient carried unit (B). The patient carried unit includes an amplitude modulation algorithm such as a look-up table ( ), a pulse width modulation algorithm ( ), and an interpulse interval modulation algorithm ( ). The algorithms derive corresponding stimulus pulse train parameters from the proportional signal which parameters are transmitted to an implanted unit (D). The implanted unit has a power supply ( ) that is powered by the carrier frequency of the transmitted signal and stimulation pulse train parameter decoders ( ). An output unit ( ) assembles pulse trains with the decoded parameters for application to implanted electrodes (E). A laboratory system (C) is periodically connected with the patient carried unit to measure for changes in patient performance and response and reprogram the algorithm accordingly. The laboratory system also performs initial examination, set up, and other functions.

Functional neuromuscular stimulation system

An input command controller (A) provides logic function selection signals and proportional signals. The signals are generated by movement of a ball member (12) and socket member (14) relative to two orthogonal axes. When the joystick is implanted, a transmitter (50) transmits the signals to a patient carried unit (B). The patient carried unit includes an amplitude modulation algorithm such as a look-up table (124), a pulse width modulation algorithm (132), and an interpulse interval modulation algorithm (128). The algorithms derive corresponding stimulus pulse train parameters from the proportional signal which parameters are transmitted to an implanted unit (D). The implanted unit has a power supply (302) that is powered by the carrier frequency of the transmitted signal and stimulation pulse train parameter decoders (314, 316, 318). An output unit (320) assembles pulse trains with the decoded parameters for application to implanted electrodes (E). A laboratory system (C) is periodically connected with the patient carried unit to measure for changes in patient performance and response and reprogram the algorithm accordingly. The laboratory system also performs initial examination, set up, and other functions.

An input command controller provides logic function selection signals and proportional signals. The signals are generated by movement of a ball member and socket member relative to two orthogonal axes. When the joystick is implanted a transmitter transmits the signals to a patient carried unit. The patient carried unit includes an amplitude modulation algorithm such as a look-up table, a pulse width modulation algorithm, and an interpulse interval modulation algorithm. The algorithms derive corresponding stimulus pulse train parameters from the proportional signal which parameters are transmitted to an implanted unit. The implanted unit has a power supply that is powered by the carrier frequency of the transmitted signal and stimulation pulse train parameter decoders. An output unit assembles pulse trains with the decoded parameters for application to implanted electrodes. A laboratory system is periodically connected with the patient carried unit to measure for changes in patient performance and response and reprogram the algorithm accordingly. The laboratory system also performs initial examination, set up, and other functions. A percutaneous interface structure is provided which facilitates cleansing the area of the limb around the electrode leads, which protects the lead wires from damage and catching and which protects the patient against catching the lead wires and pulling or ripping the electrodes form the implantation site.

Growing community of inventors

Cleveland Heights, OH, United States of America

Paul Hunter Peckham