Fresenius Medical Care Deutschland Gmbh

Raimung Margreiter

Paul Hengster

Massimo Earl Fini

Franz Kugelmann

Ciro Tetta

Michael Paul

Marco Caronna

Bernd Nederlof

Thomas Wild

Micaela Yakubovich

Boris-Wolfgang Hochleitner

Raimund Margreiter

A reactor has a reactor unit with a first chamber and a second chamber, with the first chamber being formed by the interior of a housing and the second chamber being formed by the interior of a plurality of hollow fibers arranged in the housing. The hollow fibers are arranged in the housing such that their density in at least one region of the first chamber does not exceed 10 fibers/mm, based on the cross-sectional area of the first chamber. The reactor unit can include two casting compounds, in which a portion of the hollow fibers are embedded and between which another portion of the hollow fibers extends. The length of at least some or all of the hollow fibers is at least 0.5% greater than the distance of the casting compounds.

Reactor and reactor unit with hollow fibers

The bioartificial reactor has a reactor vessel. A cell culture chamber in the reactor, in particular for liver cells, is divided off from a flow chamber for a nutritive medium and from a flow chamber for plasma and blood by semipermeable walls. At least one flow chamber is formed as a tube that is helically wound in the shape of a screw and that is made of semipermeable material.

Bioartificial device for the storage, cultivation and/or multiplication of cells

Growing community of inventors

Innsbruck, Austria

Paul Hengster