Pacific Biosciences of California, Inc.

Complete Genomics, Inc.

Apton Biosystems, Inc.

Paul Heilman

Bryan P Staker

Windsor Owens

Edvinas Zizminskas

David Stern

Robert Hartlage

Rob Hartlage

Jim Jahncke

Disclosed herein is a high throughput optical scanning system to generate super resolution images and methods of use. The optical scanning device and methods of use provided herein can allow high throughput scanning of a continuously moving object with a high resolution despite fluctuations in stage velocity. This can aid in high throughput scanning of a substrate, such as a biological chip comprising fluorophores. Also provided herein are improved optical relay systems and scanning optics.

High speed scanning systems for super resolution imaging

Disclosed herein is a high throughput optical scanning device and methods of use. The optical scanning device and methods of use provided herein can allow high throughput scanning of a continuously moving object with a high resolution despite fluctuations in stage velocity. This can aid in high throughput scanning of a substrate, such as a biological chip comprising fluorophores. Also provided herein are improved optical relay systems and scanning optics.

High speed scanning system with acceleration tracking

An array chip design is provided where the chip includes a field region arranged with sites according to a first pitch and at least one track region having a one-dimensional site pattern arranged according to a second pitch that is less dense and is an integer multiple of the first pitch so that observation through pixel-based sensors using one-dimensional quad-cell averaging can be applied in the track region, thereby to attain alignment of the chip to pixel-based optical instrumentation with a higher density of sites.

High-density devices with synchronous tracks for quad-cell based alignment correction

Growing community of inventors

San Carlos, CA, United States of America

Paul Heilman