Lionheart Technologies, Inc.

Bio-tek Holdings, Inc.

Paul G Held

David Schneider

Paula B Tracy

Norman R Alpert

Paul D Hale

Burton E Sobel

The present invention provides a method for the quantification and assessment of platelet activation in whole blood samples and monitoring of antiplatelet pharmacologic agents. The method for quantifying platelet activation includes exposing platelets to a physiological concentration of an agonist that activates some of the platelets, resulting in the formation of at least one binding site on the surface of the activated platelets, and measuring the activated platelets. The present invention provides a method of assessing specific components of platelet activation.

Method for determining platelet reactivity in a whole blood sample

A system for performing vertical spectrophotometric determinations uses a vessel which has an upper transparent surface and a lower transparent surface which are spaced apart to define a known fixed pathlength through which a light beam is transmitted. The vessel also includes a portion disposed above the upper surface which may be a spout having an opening for allowing the introduction of substances into the containment portion.

Method of and apparatus for performing fixed pathlength vertical

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Burlington, VT, United States of America

Paul G Held