Synthelabo

Paul Fabiani

Christian J Warolin

Abkar Vartanian

Francis Rose

2,3-Dihydro-imidazo[1,2-b]pyridazine derivatives of the formula: ##STR1## in which R.sub.1 represents a phenyl, halogenophenyl, trifluoromethylphenyl, C(.sub.1-4)-alkylphenyl, (C.sub.1-4)-alkoxyphenyl, hydroxyphenyl, nitrophenyl, aminophenyl, (C.sub.1-4)-alkylaminophenyl, di-(C.sub.1-4)-alkylaminophenyl, acetamidophenyl, thienyl, pyridyl, furyl or nitrofuryl radical, R.sub.2 represents a hydrogen atom or a (C.sub.1-4)-alkyl radical, and R.sub.3 represents a hydrogen atom or a (C.sub.1-4)-alkyl, phenyl, halogenophenyl, trifluoromethylphenyl, (C.sub.1-4)-alkylphenyl, (C.sub.1-4)-alkoxyphenyl, hydroxyphenyl, nitrophenyl, aminophenyl, (C.sub.1-4)-alkylaminophenyl, di-(C.sub.1-4)-alkylaminophenyl or acetamidophenyl radical, and its addition salts with pharmaceutically acceptable acids are useful in therapy as antidepressants. They may be made by cyclization of compounds of the formula: ##STR2##

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Paul Fabiani