Vanderbilt University

Paul Edward Laibinis

Richard Caprioli

Jeremy L Norris

Junhai Yang

Faizan Zubair

Pre-coated analysis substrates, and methods of making the substrates and using them to analyze animal tissue, are described. The pre-coated analysis substrates can be made by forming a matrix surface on an analysis substrate; adding a protease to the matrix surface to form a pre-coated analysis substrate; and placing an animal tissue specimen on the matrix surface. The animal tissue can then be analyzed by allowing the protease to partially digest the animal tissue specimen; and analyzing the partially digested animal tissue specimen by mass spectrometry.

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Brentwood, TN, United States of America

Paul Edward Laibinis