Volcano Corporation

Philips Image Guided Therapy Corporation

Cardiometrics, Inc.

Pharmasonics, Inc.

Other

Diasonics, Inc.

Hewlett-packard Company

Endosonics Corporation

Volcano Therapeutics, Inc.

Keimar Corporation

Cardiometric, Inc.

Park, Jinhyoung

Corl, Paul Douglas

Paul Douglas Corl

John Ortiz

Jerome Segal

John R McKenzie

Jeffrey J Christian

Menahem F Nassi

Robert Obara

Ronald G Williams

Bret Millett

Axel F Brisken

David H Burkett

Mark W Cowan

Robert F Zuk

Wayne C Haase

Victor Chechelski

Ilan Lifshitz

Vincent A Barletta

Michael C Pao

David G Miller

Joseph Karratt

Robert Z Obara

Gordon S Kino

Gary B Hulme

Paul M Hoseit

Jeffrey S Frisbie

Henry L Schwartz

Douglas Meyer

Anthony J Rossetti

David M Kaiser

Jinhyoung Park

Michael Reiter

Amos Gottlieb

Dylan Van Hoven

Joe R Suarez

Harry D Nguyen

Margaret R Webber

Peter M Grant

Georg Teslawski

Jeffrey H Brown

Wayne C Hasse

Ronald G William

Jeffrey S Frisble

Bret C Millett

The present disclosure involves a medical device. The medical device includes an elongate cable assembly having a distal connector, a proximal connector, and a cable body coupling the proximal and distal connectors. The distal connector is configured for coupling with a diagnostic medical device. The proximal connector is configured for coupling with a medical measurement system. An electronic component is located inside the distal connector or the associated cable housing. The electronic component includes an analog-to-digital converter (ADC) and a microprocessor. The ADC is configured to receive medical data gathered by the diagnostic medical device and convert the medical data into digital signals. The microprocessor is coupled to an output of the ADC and configured to process the digital signals into a format that is readable by the medical measurement system.

Smart interface cable for coupling a diagnostic medical device with a medical measurement system

An intravascular pressure sensor assembly is disclosed herein that is produced in part using photolithography and DRIE solid-state device production processes. Using DRIE production processes facilitates a number of features that could not be readily incorporated in sensor chips fabricated using mechanical saws. In accordance with a first feature, sensor chips are created with non-rectangular outlines. The sensor chip includes a widened portion that substantially abuts an inner wall of a sensor housing, and a cantilevered portion that is relatively narrow in relation to the widened portion. The non-rectangular outline of the sensor chip is formed using photolithography in combination with DRIE processing. In accordance with another feature, the sensor chip is positioned width-wise in the housing, thereby reducing a required length for the housing. In accordance with yet another feature, the sensor chip comprises one or more cutouts for receiving signal wires for connection to signal lead lines on the sensor chip. The outline of the sensor chip and the cutouts are formed using photolithography in combination with DRIE processing.

Intravascular pressure devices incorporating sensors manufactured using deep reactive ion etching

Sold-state intravascular ultrasound (IVUS) imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to compact and efficient circuit architectures and electrical interfaces for an ultrasound transducer array used in a solid-state IVUS system. In one embodiment, an intravascular ultrasound (IVUS) device includes: a flexible elongate member; an ultrasound scanner assembly disposed at a distal portion of the flexible elongate member, the ultrasound scanner assembly including an ultrasound transducer array; an interface coupler disposed at a proximal portion of the flexible elongate member; and a cable disposed within and extending along a length of the flexible elongate member between the ultrasound scanner assembly and the interface coupler. The cable includes four conductors electrically coupling the ultrasound scanner assembly and the interface coupler.

Intravascular ultrasound imaging apparatus, interface architecture, and method of manufacturing

Embodiments of the present disclosure are related to intravascular devices having improved rapid-exchange configurations and associated systems and methods. In some particular embodiments, the devices of the present disclosure include a reinforced rapid-exchange port, an offset rapid-exchange port, and/or combinations thereof. For example, in some implementations an intravascular imaging device is provided that includes a main catheter body; a rotational imaging element positioned within a lumen of the main catheter body; a distal portion extending from the main catheter body, the distal portion having a rapid-exchange port in communication with a guidewire lumen, the rapid-exchange port and the guidewire lumen sized and shaped to receive a guidewire; and at least one reinforcing element positioned adjacent to the rapid-exchange port.

Intravascular devices having reinforced rapid-exchange ports and associated systems and methods

Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries by monitoring fluid flow. In some embodiments, the devices, systems, and methods of the present disclosure receive analog sensor data that includes fluid flow data and digitizes the analog sensor data according to a quadrature sampling rate. A weighted accumulator performs a baseband conversion on the digitized sensor data and may perform other signal processing steps. The processed data is then provided for use in any one of a number of diagnostic assessments.

Sensor interface device providing digital processing of intravascular flow and pressure data

A field programmable gate array (FPGA) circuit including a quadrature internal conditioning circuit is provided. The circuit having a buffer circuit; and a reconstruction engine circuit, wherein the reconstruction engine circuit includes: a circuit to measure a phase of a signal; and a flavor interpolation circuit; wherein: the circuit to measure the phase of a signal includes digitization points forming two complex numbers for each cycle of the center frequency of the signal. A system for collecting tissue images including a patient interface module (PIM); a pulse transmitter circuit; an analog to digital converter circuit; and an FPGA circuit as above; and a catheter having a sensing head is also provided. A method for using the above system to provide an image reconstruction is also provided.

Synthetic aperture image reconstruction system in a patient interface module (PIM)

An ultrasound transducer for use in intravascular ultrasound (IVUS) imaging systems including a single crystal composite (SCC) layer is provided. The transducer has a front electrode on a side of the SCC layer; and a back electrode on the opposite side of the SCC layer. The SCC layer may have a bowl shape including pillars made of a single crystal piezoelectric material embedded in a polymer matrix. Also provided is an ultrasound transducer as above, with the back electrode split into two electrodes electrically isolated from one another. A method of forming an ultrasound transducer as above is also provided. An IVUS imaging system is provided, including an ultrasound emitter and receiver rotationally disposed within an elongate member; an actuator; and a control system controlling emission of pulses and receiving ultrasound echo data associated with the pulses. The ultrasound emitter and receiver include an ultrasound transducer as above.

Focused rotational IVUS transducer using single crystal composite material

An intravascular ultrasound probe is disclosed, incorporating features for utilizing an advanced transducer technology on a rotating transducer shaft. In particular, the probe accommodates the transmission of the multitude of signals across the boundary between the rotary and stationary components of the probe required to support an advanced transducer technology. These advanced transducer technologies offer the potential for increased bandwidth, improved beam profiles, better signal to noise ratio, reduced manufacturing costs, advanced tissue characterization algorithms, and other desirable features. Furthermore, the inclusion of electronic components on the spinning side of the probe can be highly advantageous in terms of preserving maximum signal to noise ratio and signal fidelity, along with other performance benefits.

Rotational intravascular ultrasound probe with an active spinning element

Solid-state ultrasound imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to compact and efficient ultrasound transducer scanner formed from a substantially cylindrical semiconductor substrate. In some embodiments, an intravascular ultrasound (IVUS) device includes: an ultrasound scanner assembly disposed at a distal portion of the flexible elongate member, the ultrasound scanner assembly including a semiconductor substrate having a plurality of transistors formed thereupon. The semiconductor substrate is curved to have a substantially cylindrical form when the ultrasound scanner assembly is in a rolled form, and the plurality of transistors are arranged in a cylindrical arrangement when the ultrasound scanner assembly is in the rolled form. In one such embodiment, the device further includes a plurality of ultrasound transducers formed upon the semiconductor substrate and arranged in a cylindrical arrangement when the ultrasound scanner assembly is in the rolled form.

Embodiments of the present disclosure are related to intravascular imaging devices having a low reverberation housing and associated systems and methods. In some particular embodiments, the devices of the present disclosure include a transducer housing having a trough on the backside of the ultrasound transducer to deflect ultrasound signals away from the ultrasound transducer. For example, in some implementations an intravascular imaging device is provided that includes a catheter body; a drive cable extending through a lumen of the catheter body; a housing coupled to a distal section of the drive cable; and an ultrasound transducer mounted within the housing, wherein the housing includes a trough on a backside of the ultrasound transducer, the trough shaped to deflect ultrasound signals away from the ultrasound transducer. Methods of making such devices and systems are also provided.

Intravascular imaging devices having a low reverberation housing and associated systems and methods

Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices are guide wires that include a capacitive pressure-sensing component disposed at a distal portion of the guide wire. Methods of making such intravascular devices, including various manufacturing and assembling techniques, are disclosed. Systems associated with such intravascular devices and methods of using such devices and systems are also disclosed.

Capacitive intravascular pressure-sensing devices and associated systems and methods

Growing community of inventors

Palo Alto, CA, United States of America

Paul Douglas Corl