Pharmacia & Upjohn Company

Zoetis Services LLC

Warner-lambert Company

Zoetis LLC

Paul D Johnson

Richard Andrew Ewin

Rajendran Vairagoundar

Graham M Kyne

Paul A Aristoff

Gordon L Bundy

Joseph Walter Strohbach

Ronald B Gammill

Harvey I Skulnick

Suvit Thaisrivongs

David John Anderson

Michael P Curtis

Steven Ronald Turner

Karen Rene Romines

Todd M Maddux

Tomasz Respondek

Matthew W Bedore

Jackson B Hester, Jr

Michael R Barbachyn

Jacob Bradley Schwarz

Ruben Alberto Tommasi

Timothy Allan Johnson

Joel Morris

Susan M K Sheehan

Louis L Skaletzky

Mark Stephen Plummer

Brian A Duclos

Timothy Thomas Curran

Michael J Genin

Augustine Tobi Osuma

Ji Zhang

Mark R Cox

Norman Lloyd Colbry

Tom L McTier

Peter Garth Blazecka

Kevin Edward Henegar

Theresa M Schwartz

George P Luke

Garrett Hoge

Annise Paige Goodman

Derek Clinton Vrieze

Joseph Richard Bozelak

Susan M Sheehan

Richard Charles Thomas

Edmund Lee Ellsworth

Toni-Jo Poel

Lisa Marie Thomasco

Derek James Sheehan

Donald James Skalitzky

Fred L Ciske

Paul K Tomich

Susan Mary Kult Sheehan

Michael John Bohanon

Christopher Scott Knauer

Lee S Banitt

Qingwei Zhang

Chih-Ping Yang

Christoper S Knauer

Denis Billen

Michael Curtis

Richard M Goodwin

Andrea K Haber-Stuk

Defined herein are immunomodulating Formula (1) compounds wherein R, R, R, R,

Immunomodulating urea azalides

The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R, R, R, R, L, and L, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.

Endoparasitic depsipeptides

The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R, R, R, R, L, and Lare as defined herein. The present invention also contemplates compositions, methods of treatment, and uses as a medicament to treat an animal for an endoparasitic infection with a Formula (1) compound.

Defined herein are immunomodulating Formula (1) compounds wherein R, R, R, R, Rand W are as defined herein, stereoisomers thereof, and pharmaceutically acceptable salts thereof; and compositions comprising said compounds. The invention also includes methods for treating an inflammatory and/or immunological disease or disorder in an animal by administering a therapeutically effective amount of a Formula (1) compound, stereoisomer thereof, and a pharmaceutically acceptable salt thereof; or use of said compound of Formula (1) to prepare a medicament for treating an inflammatory and/or immunological disease or disorder in an animal.

The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical compositions containing these novel compounds, and methods for the preparation of these compounds.

Phenicol antibacterials

The present invention provides novel cephalosporin derivatives of formula I, 

Cephalosporins useful as antibacterial agents

Certain &#x3b2;-amino acids that bind to the alpha-2-delta (&#x3b1;2&#x3b4;) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. Also disclosed are methods of making the &#x3b2;-amino acids.

Amino acids with affinity for the &#x3b1;2&#x3b4;-protein

The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents.

Oxazolidinones having a benzannulated 6-  or 7-membered heterocycle

Bicyclic isoxazolinones as antibacterial agents

Bicyclic oxazolidinones as antibacterial agents

The present invention relates to compounds of formula I and II which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4-hydroxy-cycloalkyl&lsqb;b&rsqb;pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus.

Compounds useful to treat retroviral infections

Pyranone compounds useful to treat retroviral infections

4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl�b!pyran-2-ones

Growing community of inventors

Kalamazoo, MI, United States of America

Paul D Johnson