University of Florida Research Foundation Inc

Convergent Engineering, Inc.

Other

Airon Corporation

Paul Bradford Blanch

Michael Joseph Banner

Neil R Euliano

Richard Joel Melker

Samsun Lampotang

Jose Carlos Principe

Victor L Brennan

Ronald G Carovano

Vikas V Meka

Neil Russell Euliano, Ii

Johannes Hugo Van Oostrom

Jeffrey W Skimming

Aneel Rijhwani

Neil Russell Euliano

Neil Russell Ii Euliano

The present invention describes a method and apparatus for detecting and quantifying intrinsic positive end-expiratory pressure (PEEPi) of a respiratory patient breathing with the assistance of a ventilator. A processing device receives respiratory airway data from one or more sensors adapted to non-invasively monitor a respiratory patient, calculates from the respiratory airway data two or more parameters that are indicative of or quantify intrinsic positive end-expiratory pressure of the patient, and generates an indication intrinsic positive end-expiratory pressure (PEEPi).

Method and apparatus for detecting and quantifying intrinsic positive end-expiratory pressure

A method of creating a noninvasive predictor of both physiologic and imposed patient effort of breathing from airway pressure and flow sensors attached to the patient using an adaptive mathematical model. The patient effort is commonly measured via work of breathing, power of breathing, or pressure-time product of esophageal pressure and is important for properly adjusting ventilatory support for spontaneously breathing patients. The method of calculating this noninvasive predictor is based on linear or non-linear calculations using multiple parameters derived from the above-mentioned sensors.

Method and apparatus for predicting work of breathing

A method of creating a non-invasive predictor of both physiologic and imposed patient effort from airway pressure and flow sensors attached to the patient using an adaptive mathematical model. The patient effort is commonly measured via work of breathing, power of breathing, or pressure-time product of esophageal pressure and is important for properly adjusting ventilatory support for spontaneously breathing patients. The method of calculating this non-invasive predictor is based on linear or nonlinear calculations using multiple parameters derived from the above-mentioned sensors.

The present invention describes a method and apparatus for detecting and quantifying intrinsic positive end-expiratory pressure (PEEPi) of a respiratory patient breathing with the assistance of a ventilator. A processing device receives respiratory airway data from one or more sensors adapted to non-invasively monitor a respiratory patient, calculates from the respiratory airway data two or more parameters that are indicative of or quantify intrinsic positive end-expiratory pressure of the patient, and generates a predicted quantitative value for intrinsic positive end-expiratory pressure based on the two or more parameters. The respiratory airway data is transformed into a predicted quantitative value for intrinsic positive end-expiratory pressure (PEEPi).

Embodiments of the present invention described and shown in the specification and drawings include a system and method for monitoring the ventilation support provided by a ventilator and automatically supplying a breathing gas to a patient via a breathing circuit that is in fluid communication with the lungs of the patient.

Medical ventilator and method of controlling same

A method of creating a non-invasive predictor of both physiologic and imposed patient effort from airway pressure and flow sensors attached to the patient using an adaptive mathematical model. The patient effort is commonly measured via work of breathing, power of breathing, or pressure-time product of esophageal pressure and is important for properly adjusting ventilatory support for spontaneously breathing patients. The method of calculating this non-invasive predictor is based on linear or non-linear calculations using multiple parameters derived from the above-mentioned sensors.

The present invention describes a method and apparatus for non-invasive prediction of the 'intrinsic positive end-expiratory pressure' (PEEPi) which is secondary to a trapping of gas, over and above that which is normal in the lungs; the presence of PEEPi imposes an additional workload upon the spontaneously breathing patient. Several indicators or markers are presented to detect and quantify PEEPnon-invasively The markers may include an expiratory air flow versus expiratory air volume trajectory, an expiratory carbon dioxide flow versus expiratory air volume trajectory, an expiratory carbon dioxide volume to expiratory air volume ratio, an expiratory air flow at onset of inhalation, a model of an expiratory waveform, a peak to mid-exhalation airflow ratio, duration of reduced exhaled airflow, and a Capnograph waveform shape.

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Embodiments of the present invention described and shown in the specification and drawings include a system and method for monitoring the ventilation support provided by a ventilator that is supplying a breathing gas to a patient via a breathing circuit that is in fluid communication with the lungs of the patient.

Ventilator monitor system and method of using same

A method and apparatus for operating a ventilator in a primary electronic mode or in a back-up pneumatic mode during primary electronic mode failure. A method and apparatus for operating a ventilator in an advanced mode, having a number of ventilatory modes, or in a basic mode, having a limited number of ventilatory modes is also disclosed.

Hybrid microprocessor controlled ventilator unit

An endotracheal tube pressure monitoring system for an endotracheal tube having at least pressure sensor in communication with a major lumen of the endotracheal tube, and a pressure monitoring subsystem in operative communication with the pressure sensor. The system may also have at least one fluid pressure line in fluid communication with the major lumen and in operative communication with the pressure monitoring subsystem to monitor the pressure of fluid within each respective fluid pressure line, and a purging subsystem in fluid communication with the fluid pressure line. Each fluid pressure line that is in fluid communication with the purging subsystem being selectively purged by the purging subsystem when pressure monitoring subsystem determines the respective pressure line has become obstructed. Purging the fluid pressure line maintains the patency of the pressure line so that accurate pressure measurements within the endotracheal tube can be obtained for calculation of parameters in lung mechanics. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 C.F.R. &#xa7;1.72(b).

Endotracheal tube pressure monitoring system and method of controlling same

Ventilatory method utilizing body length-based parameter calculations

A method and corresponding medical ventilator for nullifying the work of breathing imposed by the ventilation breathing apparatus during ventilation support of a patient having a source of breathing gas, a pressure sensor, a microprocessor, at least one actuator of a pneumatic system, and driver circuits. The medical ventilator is in fluid communication with the source of breathing and an endotracheal tube which is in fluid communication with the lungs of the patient. At least one driver circuit adjusts at least one actuator to change the supply of the breathing gas. The pressure sensor measures the pressure of the gas proximate the distal end of the endotracheal tube and generates an output based on the sensed pressure. The microprocessor controls the supply of the breathing gas exiting the pneumatic system of the ventilator and is electrically coupled to the output of the pressure sensor. The microprocessor compares the output of the pressure sensor to a predetermined baseline pressure that is greater than zero and, as a result, adjusts the actuator so that the pressure of the gas proximate the distal end of the endotracheal tube is maintained at the predetermined baseline pressure.

Method and apparatus for nullifying the imposed work of breathing

The present invention provides a system and method for monitoring the ventilation support provided by a ventilator that is supplying a breathing gas to a patient via a breathing circuit that is in fluid communication with the lungs of the patient. The ventilator has a plurality of selectable ventilator setting controls governing the supply of ventilation support from the ventilator, each setting control selectable to a level setting. The ventilator support monitor system preferably receives at least one ventilator setting parameter signal, each ventilator setting parameter signal indicative of the level settings of one ventilator setting control, monitors a plurality of sensors, each sensor producing an output signal indicative of a measured ventilation support parameter, to determine the sufficiency of the ventilation support received by the patient, and determines the desired level settings of the ventilator setting controls in response to the received ventilator setting parameter signal and the output signals. The ventilator support monitor system preferably utilizes a trainable neural netword to determine the desired level settings of the ventilator setting controls.

Growing community of inventors

Alachua, FL, United States of America

Paul Bradford Blanch