National Starch and Chemical Investment Holding Corporation

Henkel Ag & Company, Kgaa

Alza Corporation

National Starch and Chemical Corporation

Universiteit Gent

Henkel US IP Lcc

Other

Henkel IP Holding Gmbh

National Starch and Chemical Company Investment Holding Corporation

Henkel Corporation

Lts Lohmann Therapie-systeme Gmbh

Universiteit Gent Laboratorium Voor Bromatologie Faculteit Farmaceutische Wetenschappen

Paul B Foreman

Eric N Silverberg

Allison Luciano

Smita M Shah

Robert M Gale

Rama S Chandran

Jianye Wen

Jay Douglas Audett

Eli J Goldman

Jean Paul Remon

Charles Willard Paul

Yuxia Liu

Paul H Richardson

Dieter Ameye

Carmine P Iovine

Michel J N Cormier

John J Tsai

Yen-Jer Shih

Peter D Palasz

Rama V Padmanabhan

Jay Audette

Jody Voorspoels

Catherine Callens

Patrick S Eaton

Thomas Hille

Michael Timothy Philbin

James L Walker

Chris Vervaet

Jiangbo Ouyang

Paul M Petersen

Laxmisha Sridhar

James Burkert

George L Gallaway

Hock Seng Tan

Susan Lydzinski

Ingrid Zhang

Peter L Merkel

Aleksandra Dukic

Paul A Altieri

Adrianus Peter Van Veen

Laxmisha M Sridhar

Hajime Yuyama

Smita Shah

Paul Morganelli

Eric Silverberg

Jay Audett

An ultraviolet (UV) crosslinkable acrylic pressure sensitive adhesive comprises an acrylic copolymer and a cationic photoinitiator. The acrylic copolymer comprises pendant reactive functional groups. The pressure sensitive adhesive formed from the acrylic copolymer with the pendant reactive functional groups result in high green strength and/or high temperature holding strength of the adhesive.

Cationic UV-crosslinkable acrylic polymers for pressure sensitive adhesives

A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.

Transdermal nicotine salt delivery system

A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.

High enhancer-loading polyacrylate formulation for transdermal applications

An adhesive composition which lacks functional groups containing reactive hydrogen moieties and contains no post-polymerization chemical crosslinker finds use in transdermal drug delivery systems. The invention enables the administration of drugs containing a reactive functional group, which drugs have heretofore not been able to be administered by the transdermal route using conventional acrylic adhesives.

Non-reactive adhesive useful in transdermal drug delivery system

Method of making a high enhancer-loading polyacrylate formulation for transdermal applications

Silicone acrylic hybrid compositions prepared by reacting together silicone polymers, silicone resins, and silyl containing acrylic polymers are useful in adhesive compositions that find use in skin contact applications.

Silicone acrylic hybrid polymer-based adhesives

A polyacrylate formulation suitable for delivery of drug through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.

This patent pertains to the use of debranched starch in the preparation of pharmaceutical pellets by extrusion spheronization. Such excipients are useful in any dry dosage form, including tablets and capsules, for either immediate or sustained release.

Use of debranched starch in extrusion-spheronization pharmaceutical pellets

Acrylic polymers comprising vinyl acetate monomers, hydroxyl functional monomers and low Tg alkyl acrylate monomers are useful in adhesive compositions that find use in skin contact applications.

Acrylic polymer-based adhesives

Acrylic polymers comprising a non-primary hydroxyl functional monomer and low Tg alkyl acrylate monomers are useful in adhesive compositions that find use in skin contact applications.

The invention provides bioadhesive composition having increased bioadhesive properties, decreased irritation, and the capacity for higher drug loading. The compositions of the invention comprise intimate mixtures of a polysaccharide and a polycarboxylated polymer, and optionally also an absorption enhancer.

Bioadhesive composition

This invention relates to a method of producing a bioadhesive composition comprising the steps of preparing a solution of a solvent and a polymer mixture wherein the polymer mixture comprises at least one natural or synthetic polycarboxylated polymer and at least one polysaccharide; drying the solution to form a solid; and heat treating the solid to effect cross-linking and to form the bioadhesive composition.

Pressure sensitive adhesive formulations of an acrylic polymer grafted with a hydrogenated rubber. In one embodiment, the polymer contains a hydroxyalkyl (meth)acrylate ester which is crosslinked with a titanium-containing chelated metal alkoxide. The adhesive formulations provide an exceptional combination of adhesion to low energy surfaces and high temperature cohesive strength.

Rubber-acrylic adhesive formulation

Growing community of inventors

Somerville, NJ, United States of America

Paul B Foreman