Koninklijke Philips Corporation N.v.

Biocartis, Nv

Innosign B.v.

Paul Arnold Van De Wiel

Roel Penterman

Sieglinde Neerken

Marc Wilhelmus Gijsbert Ponjee

Oana Mihaela Piciu

Kristiane Anne Schmidt

Ron Gill

Wilhelmus Franciscus Johannes Verhaegh

Hendrik Jan Van Ooijen

Bart Van Meerbergen

Zeynep Seflek Unay

Bart Edward Jozef Gusta Van Meerbergen

Zeynep Seflek

Irene Dobbelaer

Bart Edward Gusta Jozef Van Meerbergen

Bart Edward Van Meerbergen

Marc Wilhelmus Ponjee

Wilhelmus Franciscus Verhaegh

The present application mainly relates to specific methods for inferring activity of a cellular signaling pathway in tissue and/or cells of a medical subject based at least on expression levels of one or more target gene(s) of the cellular signaling pathway measured in an extracted sample of the tissue and/or cells of the medical subject, an apparatus comprising a digital compressor configured to perform such methods and a non-transitory storage medium storing instructions that are executable by a digital processing device to perform such methods.

Assessment of cellular signaling pathway activity using linear combination(s) of target gene expressions

Methods and devices for detection of micro-organisms present or suspected to be present within a mammalian blood sample are provided. A selective lysis is obtained by incubating the sample in a non-ionic detergent under alkaline conditions.

Selective lysis of cells

Methods and devices for the selective lysis of cells in a sample comprising micro-organisms such as bacteria are provided. The selective lysis is obtained by incubating the sample in a non-ionic detergent under alkaline conditions.

The present invention discloses methods, kits-of-parts, and devices for the selective lysis of eukaryotic cells in a sample comprising micro-organisms such as bacteria unicellular fungi. The selective lysis is obtained by incubating the sample in an ionic surfactant under alkaline conditions.

Selective lysis of cells by ionic surfactants

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Eindhoven, Netherlands

Paul Arnold Van De Wiel