Amgen Inc.

Amgen Research (munich) Gmbh

Temic Bayern-chemie Airbag Gmbh

Paul Adam

Peter Kufer

Tobias Raum

Patrick Hoffmann

Doris Rau

Roman Kischel

Susanne Hipp

Ralf Lutterbuese

Barbara Hebeis

Eric Borges

Uwe Dolling

Peter Renn

Joachim Reif

Heinz Tillmann, Deceased

Michael Werner

The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope cluster 3 of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.

Binding molecules for BCMA and CD3

A hybrid gas generator includes a pyrotechnic gas generator joined to a high-pressure vessel which is sealed with a sealing disk composed of a substance which chemically reacts with propellant gas produced in use so that the sealing disk is opened with an advantageously reduced acoustic pressure. The propellant gas is chemically reactive and is produced from a propellant composition which is present in a surplus amount and which is composed of a propellant which is oxidizable and at least one oxidant for oxidizing the propellant. The propellant gas attacks the sealing disk chemically and thermally, and continuously burns through it to release the gas from the high-pressure vessel into a mixing chamber in the pyrotechnic gas generator.

Hybrid gas generator for filling a gas bag

Growing community of inventors

Munich, Germany

Paul Adam