Janssen Pharmaceutica Nv

The Scripps Research Institute

Other

Paul A Shanahan

Antonia Lopez-Girona

Jorge Eduardo Vialard

Paul R Russell

Michael N Boddy

Cecile-Marie D D Denis

Clare H McGowan

The present invention encompasses novel mammalian cell cycle checkpoint genes/DNA repair genes, cDNA or genomic DNA, isolated nucleic acids corresponding thereto, proteins encoded thereby, expression vectors comprising said nucleic acids, host cells transformed with said expression vectors, and methods for treating a cell using such nucleic acids or proteins.

Human and murine Mus81 proteins

The present invention encompasses novel mammalian cell cycle checkpoint genes/DNA repair genes, cDNA or genomic DNA, isolated nucleic acids corresponding thereto, expression vectors comprising said nucleic acids, host cells transformed with said expression vectors, pharmaceutical compositions and the formulation of such compositions comprising said nucleic acids or proteins expressed therefrom, methods for treating a cell using such nucleic acids, proteins or pharmaceutical compositions, and the use of such nucleic acids or proteins in formulating a pharmaceutical preparation.

Genes and proteins encoded thereby

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San Diego, CA, United States of America

Paul A Shanahan