The Dow Chemical Company

Dowelanco

Paul A Meyers

Linneaus C Dorman

A controlled release and delivery system for a hydrophobic, water sensitive herbicide is produced by:

Herbicidal latex dispersion for controlled delivery and release of

A process for the prosthetic supplementation or replacement of hard tissue. In the process an anatomically-shaped form is molded by or a prosthetic device is coated with a composite material containing unsintered calcium phosphate biomaterial, a synthetic biodegradable polymer, and optionally, a pore-forming agent.

Composites of unsintered calcium phosphates and synthetic biodegradable

A storage stable, water emulsifiable, substantially non-aqueous liquid or low melting solid concentrate adapted for on-site preparation of an aqueous emulsion of an agricultural chemical, consisting essentially of a solution, in

Emulsifiable polymer concentrate

A storage stable, water emulsifiable, substantially non-aqueous, liquid concentrate adapted for on-site preparation of an aqueous emulsion of an agricultural chemical, consisting essentially of a solution of

Emulsfiable polymer concentrate controlled delivery and release system

Composite materials useful as hard tissue prosthetics comprising synthetic biodegradable polymers and unsintered calcium phosphate biomaterials optionally porositized by pore-forming agents are described. The composite materials may be ground and blended with a compatible water soluble pore-forming agent and then molded to form dense, shaped objects which may be made porous by leaching out said water soluble pore-forming agent. The composites may be used as hard tissue prosthetics either alone or in conjunction with conventional prostheses.

An in situ polymerization process is disclosed whereby an .alpha.-amino acid N-carboxyanhydride is blended intimately and efficiently with one or more calcium phosphate biomaterials. The polymerization proceeds at ambient temperature and pressure without the need for initiators or surface modification of the calcium phosphate biomaterials. The resulting composite material may subsequently be ground and blended with a compatible water soluble pore-forming agent and then molded to form dense, shaped objects which may be made porous by leaching out said water soluble pore-forming agent. The resulting shaped objects may then be used as hard tissue prosthetics either alone or in conjunction with conventional prostheses.

Process for the preparation of hard tissue prosthetics

An in situ polymerization process is disclosed whereby an .alpha.-amino acid N-carboxyanhydride is blended intimately and efficiently with one or more calcium phosphate biomaterials. The polymerization proceeds at ambient temperature and pressure without the need for initiators or surface modification of the calcium phosphate biomaterials. The resulting composite material may subsequently be ground and blended with a compatible water soluble pore-forming agent and then molded to form dense, shaped objects which may be made porous be leaching out said water soluble pore-forming agent. The resulting shaped objects may then be used as hard tissue prosthetics either alone or in conjunction with conventional prostheses.

The present invention is directed to mineral filled .alpha.-amino acid polymer composite materials. The composite materials are prepared by the in situ polymerization of an .alpha.-amino acid N-carboxyanhydride in the presence of mineral fillers which are optionally surface-modified with a partially hydrolyzed polyoxazoline prior to said polymerization. Composite materials prepared in this manner consist of an intimate mixture of polymer and mineral filler which may be optionally blended with a crosslinking agent and then molded to produce smooth, hard homogeneous materials that are water and oil resistant and have good heat distortion properties.

Growing community of inventors

Dublin, CA, United States of America

Paul A Meyers