Harbor Branch Oceanographic Institution, Inc.

Paul A Horton

Shirley A Pomponi

Ross E Longley

Frank Koehn

Oliver J McConnell

Novel macrolide compounds, including Lasonolide A and Lasonolide B, have been isolated from a marine sponge. These compounds, analogs, derivatives, or isomers of these compounds, and compositions comprising the compounds or its derivatives, are useful as antitumor agents and as biochemical tools.

Cytotoxic macrolides and methods of use

A novel macrolide compound, lasonolide A, has been isolated from a marine sponge. This compound, derivatives of the compound, and compositions comprising the compound or its derivatives, are useful as antitumor agents and as biochemical tools.

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Vero Beach, FL, United States of America

Paul A Horton