Medtronic, Inc.

St. Jude Medical, Cardiology Division, Inc.

Imperception, Incorporated

Other

St. Jude Medical International Holding S.a.r.l.

Paul A Belk

David Arthur Casavant

Thomas J Mullen

John Charles Stroebel

Todd Jon Sheldon

Troy Edward Jackson

Michael O Sweeney

Wade M Demmer

Robert A Betzold

Karen J Kleckner

Scott A Kramer

Erich W Stoermer

Gene A Bornzin

Douglas A Hettrick

Zoltan Somogyi

Charles Dennis Swerdlow

Douglas A Peterson

Steven R Hornberger

Amy L Hanenburg

Joshua C Conway

Emily Weiss

Jeffrey M Gillberg

Jian L Cao

Scott R Stanslaski

Mark L Brown

Theodore Paul Dale

Daniel Coyle

Anthony David Hill

Jennifer Heisel

John C Rueter

Paul J DeGroot

Yuriy Malinin

Trent M Fischer

Daniel Robert Kaiser

Cable Patrick Thompson

Linda L Ruetz

David James Broman

Maxim Yoresh

Eric Lundquist

Gavin P Seeker

Juan Carlos Tantalean, Ii

Amy L Hanenberg

Jennifer M Heisel

Michael D Sweeney

Robert A Betzhold

A delivery device for delivering a pacing lead to the His bundle of a patient's heart includes an elongated sheath having a distal end, and a plurality of mapping electrodes positioned at the distal end. The distal end of the sheath may have a distal tip, and the mapping electrodes may include two electrodes that diametrically oppose one another at a position spaced from the distal tip of the sheath. The sheath includes a plurality of flexible sections spaced apart from one another, and a pull wire that causes the sheath to deflect from a straight configuration to a dual hinged curved configuration that positions the electrodes in the vicinity of the bundle of His.

Deflectable mapping guide sheath for his bundle pacing

Systems and methods are described for implementing a catheter model to estimate shape of a deformable catheter in a three-dimensional space. The catheter model includes two or more model segments that correspond to two or more segments of the deformable catheter. Each model segment includes a length and location of model electrode(s) and/or model magnetic sensor(s) corresponding electrodes and/or magnetic sensors of the deformable catheter. Variable shape parameter define a curvature of the segment. Varying the shape parameters generates a plurality of potential catheter shapes. In conjunction with generating the potential catheter shapes, impedance and/or magnetic responses (e.g., measured responses) are obtained for the physical electrodes and/or physical magnetic sensors of the deformable catheter. Using a selected one (e.g., most likely) of the potential catheter shapes and the measured responses, the shape parameters are updated and a catheter shape is generated and displayed.

Mechanical modules of catheters for sensor fusion processes

The present disclosure provides improved leadless pacemakers. In one embodiment, the leadless pacemaker includes an implantable pulse generator releasably coupled to a collapsible anchoring device. The collapsible anchoring device includes at least one pacing electrode configured to contact tissue at a target site.

Leadless pacemaker with collapsible anchoring device

An electro-anatomical model of the mammalian His/Purkinje system includes a shell simulating the anatomy of at least a portion of a mammalian heart. The shell has a hollow interior and a first port providing an aperture to the interior of the shell. A plug is inserted in the first port so that a surface of the plug is exposed to the interior of the shell. An electrical circuit provides signals to electrodes in the plug which simulate the electrical signals generated by the bundle of His/Purkinje system in vivo. A second port provides access to the interior of the shell for an introducer catheter to locate the simulated bundle of His and to insert a pacing lead therein. The model is useful for developing tools for His pacing and for training users in techniques for implanting His pacing leads.

Realistic electro-anatomical model of the mammalian His/Purkinje system

A medical device performs a method for computing an estimate of a physiological variable. The method includes sensing a physiological signal and measuring an event of the physiological signal. The device initializes a value of a long-term metric of the event measurement, wherein the long-term metric corresponds to a time interval correlated to a response time of the physiological variable to changes in the event. The estimate of the long-term metric is updated in a memory of the medical device using a previous long-term metric and a current measurement of the event. The device detects a need for computing the physiological variable and computes an estimate of the physiological variable using the updated long-term metric.

Method for calculating an estimate of a time-varying physiological variable

A catheter includes an inflation balloon and at least one electrode. The inflation balloon is inflatable within a vessel. The at least one electrode extends around at least a portion of a periphery of the inflation balloon. The at least one electrode is expandable as the inflation balloon is inflated, and contracts as the inflation balloon is deflated. The at least one electrode is held in place along a length of the inflation balloon with a tether member, which is secured at opposing distal and proximal ends of the inflation balloon.

Apparatuses and methods for affixing electrodes to an intravascular balloon

Cardiac pacing methods for an implantable single chamber pacing system, establish an offset rate for pacing at a predetermined decrement from either a baseline rate (i.e. dictated by a rate response sensor), or an intrinsic rate. Pacing maintains the offset rate until x of y successive events are paced events, at which time the offset rate is switched to the baseline rate for pacing over a predetermined period of time. Following the period, if an intrinsic event is not immediately detected, within the interval of the offset rate, the rate is switched back to baseline for pacing over an increased period of time. Some methods establish a preference rate, between the offset and baseline rates, wherein an additional criterion, for switching from the offset rate to the baseline rate, is established with respect to the preference rate.

Methods for promoting intrinsic activation in single chamber implantable cardiac pacing systems

A preferred atrial-based pacing method and apparatus is provided using an intelligent cardiac pacing system to having the ability to continue atrial-based pacing as long as relatively reliable AV conduction is present. In the event that such relatively reliable AV conduction is not present, mode switching to a DDD/R or a DDI/R pacing mode while continually biased to mode switch back to atrial-based pacing. The standard or relatively reliable AV conduction may be changed either automatically or manually. This increases pacing that utilizes natural AV conduction however possible so as to gain all the benefits of cardiac contractile properties resulting therefrom, while tolerating the occasional missed ventricular depolarization (i.e., non-conducted P-wave). In the event where relatively reliable AV conduction is not present, the pacing mode is switched to a DDD/R mode while detecting a return of the relatively reliable AV conduction (and resulting mode switch to preferred atrial based pacing).

Preferred ADI/R: a permanent pacing mode to eliminate ventricular pacing while maintaining backup support

An implantable medical device and associated method provide atrial pacing and measure an atrial ventricular (AV) delay. An autonomic function index is computed using the AV delay. The autonomic function index may be compiled in a medical report. In some embodiments, the autonomic function index is used to adjust atrial pacing control parameters.

Algorithm to modulate atrial-ventricular delay and rate response based on autonomic function

A method and device for delivering anti-tachycardia pacing (ATP) therapy that includes an electrode to sense cardiac signals and to deliver the therapy, sensing circuitry, electrically coupled to the electrode, to detect the tachycardia event in response to the sensed cardiac signals, and a processor to control delivery of the therapy. The processor determines whether a return cycle length generated subsequent to the delivery of the first plurality of pacing pulses is greater than a cycle length associated with the tachycardia event and less than a sum of the cycle length associated with the tachycardia event and a total prematurity associated with the first plurality of pacing pulses, and adjusts delivery of a second plurality of pacing pulses in response to the return cycle length being greater than the cycle length associated with the tachycardia event and less than the sum of the cycle length associated with the tachycardia event and the total prematurity associated with the first plurality of pacing pulses.

Method and device for delivering anti-tachycardia pacing therapy

Growing community of inventors

Maple Grove, MN, United States of America

Paul A Belk