Hoffmann-La Roche Inc.

Roche Molecular Systems, Inc.

Patti E Gravitt

Robert M Resnick

M Michele Manos

Catherine E Greer

Heidi M Bauer

Tracy Y Zhang

Tracy Yi Zhang

Chaka C Impraim

The presence of human papillomavirus (HPV) in a sample can be detected and the HPV typed by a method that involves the amplification of HPV DNA sequences by the polymerase chain reaction (PCR). The primers used in the method are consensus primers that can be used to amplify a particular region of the genome of any HPV. The presence of HPV in a sample is indicated by the formation of amplified DNA. The HPV nucleic acid is detected by consensus probes that may be short oligonucleotide probes or long generic probes. The HPV is typed by the use of type-specific DNA probes specific for the amplified region of DNA.

Detection of human papillomavirus by the polymerase chain reaction

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Oakland, CA, United States of America

Patti E Gravitt