E.i. Dupont De Nemours and Company

Patti Ann Parziale

Lynn E Applegate

Tzu-Ching Chang

Wayne Craig Appleton

Process for preparing 2-amino-4,6-dichloropyrimidine

Process for preparing 2-(4-thiazolyl)-1H-benzimidazole (generic name: thiabendazole) by the acid-catalyzed condensation of o-phenyldiamine and 4-cyanothiazole in solution in water or mixtures of water with miscible co-solvents (solvents which upon mixing with water in all proportions form a homogeneous mixture, as well as, other partially miscible solvents which upon mixing with water in some proportions form a homogeneous mixture under the reaction conditions of the process of this invention).

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Wilmington, DE, United States of America

Patti Ann Parziale