Orion Corporation

Patrik Holm

Gerd Wohlfahrt

Harri Salo

Arja Karjalainen

Olli Törmäkangas

Sirpa Rasku

Anniina Vesalainen

Iisa Höglund

Pia Koivikko

David Din Belle

Petteri Rummakko

Arto Tolvanen

Arto Karljalainen

Terhi Heikkinen

Riina Arvela

Peteris Prusis

Mattias Roslund

Pia Knuuttila

Lisa HÖGLUND

The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof. 

Androgen receptor modulating compounds

The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.

Compounds of formula I, wherein A, B, X, Z and R-R, are as defined in the claims, exhibit TRPA 1 activity and are thus useful as TRPA1 modulators. 

N-prop-2-ynyl carboxamide derivatives and their use as TRPA1 antagonists

2,3-dihydrobenzo[1,4] dioxin-2-ylmethyl derivatives as alpha2C antagonists for use in the treatment of peripheric and central nervous system diseases

2,3-dihydrobenzo(1,4) dioxin-2-ylmethyl derivatives as alpha2C antagonists for use in the treatment of peripheric and central nervous system diseases

2,3-dihydrobenzo(1,4) dioxin-2-ylmethyl derivatives as alpha2C antagonists for use in the treatment of peripheric and central nervous systeme diseases

Growing community of inventors

Lielahti TL, Finland

Patrik Holm