Nant Holdingsip, LLC

Abraxis Bioscience, LLC

Nantomics, LLC

Immunitybio, Inc.

Nantcell, Inc.

Other

Nantbio, Inc.

Nanthealth, Inc.

Vivorx Pharmaceuticals, Inc.

Vivorx, Inc.

Nantmobility, LLC

Nantkwest Inc.

Altor Bioscience Corporation

Tensorcom, Inc.

Nanocav, LLC

Patrick Soon-Shiong

Neil P Desai

Nicholas James Witchey

Shahrooz Rabizadeh

Kayvan R Niazi

John Wiacek

Stephen Charles Benz

John Zachary Sanborn

Paul A Sandford

Chunlin Tao

Vuong Trieu

Charles Joseph Vaske

Oleksandr V Buzko

Justin Golovato

Mark W Grinstaff

Hans G Klingemann

Kenneth S Suslick

Ravi Seshadri

Laurent H Boissel

Rahul Chaturvedi

Thomas M Wittenschlaeger

Jake Fyfe

Roswitha E Heintz

Bing Song

Kamil A Wnuk

Andrew Yang

Anthony Myers

Harsh Kupwade-Patil

Andrew Nguyen

Nathan Howard Allen

Luke Soon-Shiong

Jeremi M Sudol

Qinwei Wang

Anne-Laure Le Ny

Gary Marshall

Luna Witchey

Keaton Heinrichs

Michael Wong

Hing C Wong

Matheen M Siddiqui

David McKinnon

Orang Dialameh

Paul Weingarten

Tapas De

Harold Meherg

Shlomo Magdassi

Wenxin Xu

Emerico Alberto Brewer

Soebianto Sojomihardjo

Roswitha A Heintz

Zhiwen Yao

Jin Hyup Lee

Peter Rhode

Bai Liu

Barry J Simon

David G Ho

Clifford Anders Olson

Shiho Tanaka

Laxman Nallan

Tulay Polat

Heather McFarlane

Phillip Yang

Anne-Laure LeNy

Zachary Yim

Nicole Hensley

Leslie Louie

Elizabeth Gabitzsch

Noma R Merideth

Christopher W Szeto

Warren Marcus

Philip T Liu

Lijing You

Peter Sieling

Robert Newman

Viktor Peykov

Annie Shin

Gudmund Skjak-Braek

Chengzhi Yu

Jeffrey Safrit

Hermes J Garban

Rohit Duggal

Abhijit Dandapat

Ranjeet Sinha

Himani Chinnapen

Zaw Soe

Xiaoyun Zhu

John H Lee

Marit Otterlei

Xiaowen Sun

David T Ho

Jay Nelson

Andrew Konstantaras

Cheng Zhi Yu

Adrian Rice

Forrest Arp

Kai-Ping Han

Chihwei Chang

Qiang Yao

Terje Espevik

Tianli Zheng

Contemplated treatments and methods produce substantially increased quantities of memory T-cells and a persistent immune response by subcutaneous and/or subdermal co-administration of (1) a vector comprising a recombinant nucleic acid that encodes a cancer associated epitope, a cancer specific epitope, and/or a neoepitope, (2) an immune stimulating cytokine, and (3) a checkpoint inhibitor. Most typically, the co-administration is performed at substantially the same location, preferably within 1-21 days from each other, and the vector is an adenoviral expression vector, for example, included in a viral particle such as an AdV5 virus with a deletion of the E2b gene.

Maximizing T-cell memory and compositions and methods therefor

An example communication system includes a distributed unit of a fronthaul communication system architecture, wherein the distributed unit is in communication with a core network of the communication system, a radio unit of the fronthaul communication system architecture, wherein the radio unit is electrically coupled with at least one cellular antenna, and the radio unit is configured to transmit and receive wireless cellular signals, and a wireless communication link between the distributed unit and the radio unit. The wireless communication link includes a first system-on-chip (SoC) device electrically coupled with the radio unit, and a second SoC device electrically coupled with the distributed unit, wherein the first SoC device and the second SoC device are configured to wirelessly transmit communication signals between the radio unit and the distributed unit at a frequency of at least sixty Gigahertz.

Sixty gigahertz wireless communication systems

Techniques including data collection, organization and usage are provided, including in connection with computer-based gaming. Methods and systems are provided for establishing a set of data chronicling at least a portion of a duration of a computer-based gaming event that includes at least one user engaging in gaming using a computer or a computer-based device. Event data is obtained for chronicling chronologically ordered in-game events. Hardware and software related data is obtained that relates to the computer or the computer-based device and is relevant to the chronicling of the portion of the gaming event. Utilizing a distributed ledger technology or blockchain, the event data and the hardware and software related data are recorded in establishing the set of data chronicling at least a portion of the duration of the gaming event.

Distributed ledger tracking of event data

Techniques include minting a genesis token on a notarized ledger, the genesis token including a first pointer to an off-chain location. The techniques further include receiving new digital content related to the genesis token. The techniques further include generating a new digital token representing the new digital content. The techniques further include storing new digital token data related to the new digital token at the off-chain location. The techniques further include updating the off-chain location to include a second pointer to the new digital token. The techniques further include forming an expandable token set by linking the new digital token with the genesis token.

Efficient computer-based indexing via digital tokens, systems, methods, and apparatus

A computer-based digital token management system, comprising at least one computer readable memory storing a digital notarized ledger, a token associated with the notarized ledger, or storing software instructions. The token comprises an address field having a first portion representing an owner of the token and a second portion, different from the first portion. The system including at least one processor coupled with the at least one memory and performs the following operations: receive a request comprising token owner data and token state data to update the token, identify the token by comparing the token owner data with the first portion of the address field, generate a new address field for the token wherein at least the second portion is updated based on the token state data, and invoke a smart contract on a computing node of the notarized ledger associated with the token according to the new address field.

Managing digital blockchains via digital tokens, systems, methods, and apparatus

Systems, apparatus, and methods of managing access to private data via tokens are disclosed. The disclosed techniques provide for constructing digital tokens that represent a right-to-access private data where the tokens can be managed as individual objects. Further, such digital access tokens (DATs) can be recorded on a notarized ledger, a blockchain for example. Additionally, the rights-to-access can be embodied as a non-fungible token (NFT), which could further include support for establishing homomorphic encryption workspaces in which private data can be accessed or manipulated without exposing the private data.

Token-based digital private data exchange systems, methods, and apparatus

Techniques include receiving a request for access to the virtual token dispenser from a user device executing a gaming application. The techniques further include determining at least one user context associated with the request and based at least in part on the user device. The techniques further include identifying at least one path criterion comprising a sequence of waypoints based at least in part on the user context. The techniques further include determining satisfaction of at least one action at each waypoint in the sequence of waypoints based at least in part on a location of the user device. The techniques further include enabling presentation of the virtual token dispenser in a game session on the user device upon satisfaction of the at least one action. The techniques further include recording at least one transaction on a notarized ledger when a token is dispensed from the virtual token dispenser.

Location-based digital token management systems, methods, and apparatus

A computer-based filming production system is described. An illustrative system includes a real-world, physical environment having a set of sensors disposed about a filming volume and a production center computing system including at least one computer readable memory that enables a processor to store a prioritization policy including priorities for digital data streams and for each filming production workflow stage of a set of multiple filming production workflow stages, receive a set of sensor data representing a filming production in the filming production from the set of sensors, generate a set of digital data streams of renderable content from the set of sensor data via the filming production workflow stages and according to the priorities for each filming production workflow stage, where each digital data streams comprises prioritized rendering instructions for their respective renderable content derived from the prioritization policy, and then transmit the set of digital data streams.

Digital representation of multi-sensor data stream

Provided are methods and compositions for the treatment of cancer. The methods comprise administering to a subject an HDAC inhibitor and an immunotherapeutic agent. In certain instances the immunotherapeutic is an NK cell or a chimeric antigen receptor NK cell.

HDAC inhibitors for use with NK cell based therapies

An IL-15 super agonist (IL-15N72D:IL-15RαSU/IgG1Fc; N-803) increases circulating NK cells, effector memory and effector memory RA cells in post-allogeneic hematopoietic stem cell transplant patients (HCT). Methods of treatment include administration of N-803 to subjects in need of such treatment.

Treatment of immunosuppressed subjects

Beverage compositions and methods of preparing the same are provided herein. The beverage compositions can include calcium supplied from a calcium carbonate source including aragonite and a liquid component, such as water, a juice, a milk, and a combination thereof. Calcium components including aragonite particles and at least one additive agent as well as sweetener components including aragonite particles and at least one sweetener are also provided herein.

Beverage compositions including calcium supplied from aragonite and methods of making the same

Disclosed herein are compositions comprising oolitic aragonite particles, wherein the oolitic aragonite particles have an average particle size of between 100 nm to 1 mm, and a Hunter brightness level greater than 88. Further disclosed herein are personal care and/or cosmetic compositions, comprising a carrier and the aforementioned oolitic aragonite particles. Further disclosed herein are methods of making and using the oolitic aragonite particles.

Oolitic aragonite beads and methods therefor

Methods and systems are provided to display a real world event on a client device with avatars. Appropriate parameters for the real world event are provided and participants in the real world event are associated to avatars. As the real world event begins, a server is configured to provide information on the real world event to the client device, and the client device displays a representation of a virtual event using the avatars and the information received from the server.

Avatar-based sports betting

A method of making superhydrophobic concrete includes creating a mixture, wherein the mixture comprises aragonite and/or graphene, and heating the mixture to a temperature between 500° C. and 2,500° C., then drying the mixture, and, optionally, adding the mixture to concrete.

Hydrophobic concrete and asphalt

Growing community of inventors

Los Angeles, CA, United States of America

Patrick Soon-Shiong