Bayer Cropscience Gmbh

Bayer Intellectual Property Gmbh

Patrick Schwientek

Colleen S Taylor

Bjorn A Traag

Jeremy Beau

Daniel M Joo

Jörn Kalinowski

Alfred Pühler

Hermann Wehlmann

Klaus Selber

Winfried Rosen

Udo Wehmeier

Andreas Klein

Andreas Goertz

Bernhard Weingaertner

Donglan Tian

Adam Newman

The present invention provides a composition comprising a biologically pure culture of asp. strain or a cell-free preparation thereof comprising a fusaricidin and a tridecaptin; wherein the fusaricidin is produced with a fusaricidin synthetase gene of fusA encoded by a DNA sequence exhibiting at least 90.5% sequence identity to SEQ ID NO: 3; and the tridecaptin is produced with a nonribosomal peptide synthetase (NRPS) gene of triE encoded by a DNA sequence exhibiting at least 90.0% sequence identity to SEQ ID NO: 7. Also provided are methods of treating an agricultural plant to control a disease and methods of increasing the vigor and/or crop yield of an agricultural plant with the disclosed compositions.

Paenibacillus strains and methods for their use

The present invention relates to a composition comprising a biologically pure culture of a fungicidalsp. strain comprising a variant fusaricidin synthetase lacking a functional adenylation domain in the third module. The present invention also provides a composition comprising a biologically pure culture of a fungicidalsp. strain or a cell-free extract thereof comprising at least one Paeniserine and at least one Paeniprolixin. Also provided are isolated compounds and methods of treating a plant to control a plant disease with the disclosed compositions and compounds.

Paenibacillus strain, antifungal compounds, and methods for their use

strain, antifungal compounds, and methods for their use

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The present invention describes the DNA-sequence of the wild type genome as well as all genetic modifications which were introduced into the wild type&#x2014;and further developed strains, based thereon. Thereby the first genotypic characterization of the developed strains, including the latest production strain, has been accomplished, accounting for the major part of the invention. Furthermore, on the basis of the determined DNA-sequences, potential genes were identified and account, combined with their functional annotation, for another part of the invention. In particular, the gene- and DNA-sequences, as well as protein-sequences derived there out, contribute to the invention which were affected by mutagenic modifications throughout the strain development process, potentially contributing to the increased production yield.

Genomics of actinoplanes utahensis

The present invention is directed to an innate DNA sequence within the complete genome sequence ofsp. SE50/110 which resembles the structure of an actinomycete integrative and conjugative element (AICE). Related AICEs were used for establishing genetic manipulation tools for other bacteria in the past. In this document, we describe the unique features of the specific AICE found insp. SE50/110 which are clearly distinct from any other known AICE as a whole, but share minor parts with varying sequence similarity with other characterized AICEs from other species.

The present invention is directed to an innate DNA sequence within the complete genome sequence ofsp. SE50/110 which resembles the structure of an actinomycete integrative and conjugative element (AICE). Related AICEs were used for establishing genetic manipulation tools for other bacteria in the past. In this document, we describe the unique features of the specific AICE found insp. SE50/110 which are clearly distinct from any other known AICE as a whole, but share minor parts with varying sequence similarity with other characterized AiCEs from other species.

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Davis, CA, United States of America

Patrick Schwientek