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Centre National De La Recherche Scientifique

Université Louis Pasteur

Patrick Schultz

Charles Mioskowski

Fabrice Balavoine

Stéphane Rickling

Charles Miokowski

Cyrille Richard

The invention relates to macromolecules auto-assembled and photopolymerised around carbon nanotubes. Said macromolecules are essentially formed from rings of lipid compounds, polymerised about the nanotubes, said polymerised compounds being obtained from lipid molecules with one or two chains A, bonded to a group Z where A is a chain, CH&#x2014;(CH)&#x2014;C&#x2261;C&#x2014;C&#x2261;C&#x2014;(CH)&#x2014;, where n and m, independently=whole numbers from 1 to 16 and Z is a polar head group embodied by a &#x2014;COOH, &#x2014;CO&#x2014;NH&#x2014;Y, &#x2014;NHor N(R), where R is an alkyl with C, to Cand Y is a &#x2014;(CH)&#x2014;C(R)&#x2014;N(CH&#x2014;COOH)group with R=H, or a COOH group, where A is a single lipid chain or a group of structure (I) or (II), where R2=a COOH, or &#x2014;CO&#x2014;NH&#x2014;Ygroup with Y=a &#x2014;(CH)&#x2014;C (R)&#x2014;N(CHCOOH)group with R=H or a COOH group, where Z and Rcan also be neutral polar head groups of the sugar or polysaccharide type. The above is of application particularly to the protection and purification of nanotubes, as a hydrophobic molecule or membrane protein vector or as a molecular motor.

Macromolecules auto-assembled and photopolymerised around carbon nanotubes, a method for production and application thereof

Method for immobilizing and/or crystallizing biological macromolecules on carbon nanotubes and uses

The invention concerns molecular rods, their uses in a method for fixing and/or crystallising macromolecules, the resulting products and uses of said products in the field of materials and structural biology, in particular as biosensors or as biomaterials. Said molecular rods have a structure represented by the general formula (I) and said method essentially consists in incubating, for at least 15 minutes, a biological macromolecule in solution with a molecular rod as defined by the formula, in suitable temperature and pH conditions.

Molecular rod and uses

Growing community of inventors

Fegersheim, France

Patrick Schultz