Affymetrix, Inc.

Bio-rad Laboratories, Inc.

Raindance Technologies, Inc.

Patrick Odoy

Mark R Jones

Nathan K Weiner

Christopher Miles

Albert Bukys

David A Stura

Herman Deweerd

Eric E McKenzie

Thomas P Regan

David Bradbury

Roger DiPaolo

Joel M Katz

James T Overbeck

Tim J Woolaver

Eric Schultz

Ksenia Oleink-Ovod

Darren Roy Link

Akim Lennhoff

John A Luckey

Xinyu Li

Timothy J Woolaver

Oleinik-Ovod Ksenia

Ksenia Oleinik-Ovod

Erik Schultz

Systems and methods are provided for forming emulsions from an aqueous fluid and oil. The aqueous fluid-in-oil emulsions are useful for numerous molecular biology techniques. The system is configured to cyclically translate a chamber containing the emulsion components, along a cycle path, while maintaining the axial orientation of the chamber with respect to a horizontal plane, and without rotating the chamber.

System and method for forming an emulsion

An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.

System and method for scanning of probe arrays

System, method, and product for scanning of biological materials

Systems and methods are described that may be applied to scanning biological materials in or on probe arrays. For example, a system is described that includes a scanner that has one or more excitation sources and an emission receiving element, such as an objective lens, that receives from locations of the probe array an emission signal responsive to the excitation sources. The scanner also has a radial position generator that generates radial positions of the emission receiving element. Also included in the system is a computer memory having stored therein a plurality of position data, each representing a radial position of the emission receiving element. Also stored in the computer memory unit is a set of comparator instructions that generate a clock signal based, at least in part, on comparing one or more of the plurality of radial positions with one or more of the plurality of position data.

System, method, and product for pixel clocking in scanning of biological materials

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Rowley, MA, United States of America

Patrick Odoy