Gen-Probe, Inc.

Patrick Lynn Peterson

Matthias Jost

Tony Luu

Paul M Darby

Siobhan Miick

JoAnn Jackson

Matthew Brentnall

Provided herein are compositions, kits, and methods for detecting at least one of atcdA, tcdB, tcdC, cdtA, or cdtB nucleic acid in a sample. In son embodiments, one or more alleles of tcdC such as 117del tcdC or 184T tcdC are detected.

Compositions and methods for detecting toxigenic

There is disclosed a composition of an aqueous solution comprising, consisting or consisting essentially of a flap endonuclease, a bulking agent and an organic buffer, wherein the aqueous solution has an inorganic salt concentration of 5 mM or less and wherein the composition is substantially free of glycerol.

Dried compositions containing flap endonuclease

Provided herein are compositions, kits, and methods for detecting methicillin-resistant(MRSA) nucleic acids. In some embodiments, the compositions, kits, and methods can be used to detect one or more of type i, ii, iii, iv, v, vi, vii, viii, ix, xii, xiii, xiv, xv, or xxi SCCmec right extremity junction (MREJ) MRSA nucleic acids and one or more of mecA, mecC, and/or an additional-specific gene.

Compositions and methods for detecting

Methods, apparatuses, and systems are provided for processing a biological sample. Exemplary methods comprise transferring a swab associated with an aliquot of the biological sample into a wash liquid, wherein a first portion of the aliquot is released into the wash liquid; and transferring the swab into a carrier liquid, wherein a second portion of the aliquot is released into the carrier liquid. The methods can provide efficient transfer of analyte such as cells or nucleic acid into the carrier liquid while releasing particulate matter, viscous polymers, or other undesired material into the wash liquid. Alternatively or in addition, the methods can also release desired material into the wash liquid, e.g., cells, which can be used in applications such as culturing.

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San Diego, CA, United States of America

Patrick Lynn Peterson