The University of New Mexico

Patrick L Donabedian

David G Whitten

Eric H Hill

Ying Wang

Harry Craig Pappas

Kiran Bhaskar

Eva Yung Hua Chi

Yue Zhang

Arjun Thapa

Jonathan P Hulse

Eva Y Chi

Florencia A Monge

Matthew Creyer

Adeline Fanni

Various embodiments relate to p-phenylene ethynylene compounds as bioactive and detection agents. In various embodiments, the present invention provides a method of inducing germination of microbial spores including contacting the microbial spores with a p-phenylene ethynylene compound. In various embodiments, the present invention provides a method for detecting an enzyme, a method of protein analysis, or a method of detecting a chemical agent, including introducing a p-phenylene ethylylene compound to a composition including an enzyme substrate, and analyzing the fluorescence of the p-phenylene ethynylene compound. Various embodiments provide sensors that include a p-phenylene ethynylene compound and an enzyme substrate.

P-phenylene ethynylene compounds as bioactive and detection agents

Novel agents and theranostics for use as controllable and selective photosensitizers for the diagnosis, treatment and/or tracking of amyloid protein aggregates and amyloid diseases.

Theranostics for protein misfolding diseases

Various embodiments relate to p-phenylene ethynylene compounds as bioactive and detection agents. In various embodiments, the present invention provides a method of inducing germination of microbial spores including contacting the microbial spores with a p-phenylene ethynylene compound. In various embodiments, the present invention provides a method for detecting an enzyme, a method of protein analysis, or a method of detecting a chemical agent, including introducing a p-phenylene ethynylene compound to a composition including an enzyme substrate, and analyzing the fluorescence of the p-phenylene ethynylene compound. Various embodiments provide sensors that include a p-phenylene ethynylene compound and an enzyme substrate.

Growing community of inventors

Albuquerque, NM, United States of America

Patrick L Donabedian