Chemimage Corporation

Chemimage Technologies LLC

The United States of America As Represented by the Department of Health

Chem Lmage Corporation

Other

Cilag International Gmbh

Patrick J Treado

Matthew P Nelson

John Maier

Charles W Gardner, Jr

Robert Schweitzer

Shona Stewart

Jason Neiss

Scott Keitzer

G Steven Vanni

Joseph E Demuth

Jeffrey Cohen

Ryan J Priore

Chenhui Wang

David D Tuschel

Thomas Voigt

Heather Gomer

Julianne Wolfe

Shawna Tazik

Jihang Wang

Alyssa Zrimsek

Charles Gardner

Jeffrey Beckstead

Ryan D Smith

Juliane Wolfe

Xinghua Wang

Edgar Neil Lewis

Willem Windig

Wesley H Hutchison

Aaron G Smith

Jason Attanucci

Arash Samiei

Heather Kirschner

Alan Wilson

Ira W Levin

J Christopher Post

David A Keller

Robert J D'Agostino

Preston Manwaring

Tarik Yardibi

Serena Augustine

Arjun S Bangalore

Lindy A McClelland

Oksana Klueva

Nathaniel Gomer

Rick Beideman

Robert M Stern

Lucas P Zbur

Hugh W Hubble, Ii

Andrew Basta

Scott Keitzel

David W Caudle

Christopher T Zugates

James McGlone

Rebecca Schuler

Maxxwell A R Chatsko

Maxxwell Chatsko

Jeff Beckstead

Shashank R Deshpande

Lewis L Lanker

Emir Osmanagic

Christopher D Anderson

Aaron Smith

The instant disclosure provides for medical imaging systems that may be used in conjunction with an intraoperative medical device, such as an endoscope. Generally, the disclosed medical imaging systems include an illumination source configured to generate illuminating photons for illuminating a biological sample. An optical signal modulator is configured to separate one or more of the illuminating photons and photons that have interacted with the biological sample into a first optical signal having first multi-passband wavelengths and a second optical signal having second multi-passband wavelengths. At least one detector is configured to detect one or more of the first optical signal and the second optical signal and generate at least one image data set. A processor is configured to analyze the at least one image data set. In some embodiments, the processor is configured to differentiate between structures of the biological sample, such as between an ureter and surrounding tissue.

Molecular chemical imaging endoscopic imaging systems

Systems and methods of detecting and monitoring edema in a subject are described. The systems and methods include light sources, image detectors, filters, and processors that determine whether a subject has edema and the degree of severity. In some embodiments, the processor fuses data from more than one imaging modality.

Quantification of heart failure using molecular chemical imaging

Systems and methods for the detection of calculi in the biliary system are disclosed. The systems include an illumination source, one or more filters that filter a first set of illumination photons and a second set of illumination photons, as well as associated processors and detectors. The system is also designed to generate image data sets and generated information related to the location of the calculi.

Discrimination of calculi and tissues with molecular chemical imaging

System and method for detecting and monitoring edema in a patient are described. Initially, a patient's tissue is irradiated with light by a light source. A detector collects reflected light from the patient's tissue and generates data associated with the reflected light. A processing device receives the data and reflected light and calculates an intensity of the reflected light. The processing device then determined, based upon the intensity of the reflected light, whether the patient's tissue exhibits any symptoms of edema. Additionally, the processing device can compare a current intensity of the reflected light against historic information to monitor for any changes in a patient's edema level or severity.

Systems and methods for detecting edema by fusing hyperspectral and visible image

Systems for and methods for in situ optimization of tunable light emitting diode sources are disclosed herein. During operation, the systems and methods obtain real-time feedback from an image sensor, and that feedback is used to tune the tunable LEDs. By tuning the tunable LEDs, the best values for the LED spectral output can be selected based on the feedback from the image sensor, and an image with improved contrast is obtained. Alternatively, the amount of time to obtain an image with acceptable contrast is reduced.

Systems and methods foroptimization of tunable light emitting diode sources

An endoscope has an improved chip-on-tip configuration that includes both a first configuration of source illumination fibers and a second plurality of source illumination fibers, along with a camera chip. The combination of the camera chip and the source illumination fibers on the tip of the endoscope results in endoscopes with reduced size and weight.

Time correlated source modulation for endoscopy

A method for improved cardiac monitoring is disclosed. The method includes receiving image data from an image sensor configured for monitoring edema in a patient. Additional data is received from one or more additional sensors configured to monitor one or more factors related to cardiac activity of the patient. The received image data is fused with the received additional data from the one or more additional sensors to generate fused data set. A cardiac condition for the patient is determined based on the fused data set. A cardiac monitoring computing device and non-transitory medium are also disclosed.

Method for fusing sensor data for cardiac monitoring and devices thereof

Systems and methods for receiving data characterizing a plurality of images of a surgical region that includes a first target tissue. The plurality of images include a plurality images associated with visible light images, a plurality of images associated with a first wavelength and a plurality of images associated with the second wavelength that is different from the first wavelength. The method also includes generating a first scene by at least overlaying a first set of images of the plurality of images. The first set of images are temporally contiguous and include a first image associated with the first wavelength, a second image associated with visible light, and a third image associated with the second wavelength. The image further includes generating a second scene by at least overlaying a second set of images of the plurality of images. The second set of images are temporally contiguous.

Methods and devices for interleaved surgical imaging

Conformal vision with enhanced image processing of the outputted image is incorporated into novel applications. The conformal vision provides enhanced contrast by the combined inclusion of tunable filters and processing of the images that are generated by the detector. Furthermore, novel uses and applications of the conformal vision enable users to make determinations related to their health and wellness utilizing information provided by the conformal vision.

System and method for conformal vision

A method for multi-target detection and an apparatus for multi-target detection are capable of detecting at least two targets in real time or near real time. The real-time detection or near real time detection can be achieved by at least one of a Recipe Group Approach, an End Member Grouping Approach, and a Pixelated Grouping Based Approach.

Apparatus and methods for multi-target detection

The conformal spectral library training method (CSLTM) of the disclosure allows sets of voltages for an optical filter to be calculated by way of a direct calculation without processing large amounts of spectral information, which significantly increases the speed of processing spectral information.

Systems and methods of conformal spectral library training

In order to avoid friendly fire incidents in the combat theater, novel covert identification systems and methods of identifying friendly forces are provided. The systems include at least a spectroscopic imaging device and a marker that interact with each other by using a synchronized, predetermined filter tuning sequence. The filter tuning sequence enables interacted photons to wavelength hop according to the predetermined tuning sequence. As a result, the covert identification system allows friendly forces to clearly identify each while avoiding detection by enemy forces that employ conventional broadband and night vision sensors.

Systems and methods of covert identification

Systems and methods for in situ optimization of tunable light emitting diode sources

Medical imaging systems for use in conjunction with an endoscope are described. Generally, the medical imaging system includes an illumination source configured to generate illuminating photons. The illuminating photons are transmitted to one or more filters configured to filter a first plurality of illuminating photons and generate a first plurality of filtered photons comprising a first passband wavelength and a second plurality of filtered photons comprising a second passband wavelength. A sample is then illuminated with the first plurality of filtered photons and the second plurality of filtered photons to generate a first plurality of interacted photons and a second plurality of interacted photons. One or more detectors are configured to detect the first plurality of interacted photons and the second plurality of interacted photons and generate one or more image data sets.

Systems and methods for the detection of calculi in the biliary system are disclosed. The systems include an illumination source, one or more filters that filter a first set of illumination photons and a second set of illumination photons, as well as associated processors and detectors. The system is also designed to generates image data sets and generated information related to the location of the calculi.

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Pittsburgh, PA, United States of America

Patrick J Treado