Medlogic Global Corporation

Polymerics Gmbh

Flowers Park Ltd.

Patrick J Tighe

Leonard V Barley, Jr

Michael M Byram

Richard J Greff

Reed N Wilcox

Richard L George

W Kenn Thiess

Lane J Anderson

Linda M Barley

J Royce Renfrow

A cyanoacrylate adhesive is applied onto intact surface skin areas prone to ulceration so as to inhibit formation of surface skin ulcers.

Methods for inhibiting skin ulceration by use of cyanoacrylate adhesives

A cyanoacrylate adhesive is applied to non-suturable, non-sterile wound surfaces to protect and/or treat such surfaces, to promote wound healing and to retard infection of the wound.

Methods for treating non-suturable wounds by use of cyanoacrylate adhesives

Alkyl cyanoacrylate compositions comprising at least one alkyl cyanoacrylate, a biocompatible plasticizer (preferably an acyl trialkyl citrate wherein the acyl group contains from 2 to 4 carbon atoms and each alkyl group contains from 4 to 6 carbon atoms), and SO,as an anionic polymerization inhibitor are provided. These compositions are suitable for topical application to human skin.

Cyanoacrylate adhesive compositions

Alkyl cyanoacrylate compositions comprising at least one alkyl cyanoacrylate, a biocompatible plasticizer (preferably dioctyl phthalate), and SO.sub.2 as an anionic polymerization inhibitor are provided. These compositions are suitable for topical application to human skin.

A cyanoacrylate adhesive is applied onto surface skin areas prone to ulceration or irritation so as to inhibit irritation of the surface skin due to contact with an artificial device such as prosthetic devices, bandages, casts, etc.

Methods for reducing skin irritation from artificial devices by use of

A cyanoacrylate adhesive is applied onto skin area prone to exposure to discharge by patients suffering from incontinence so as to shield the skin from direct contact with the discharge. The adhesive can also be applied over medicament that has been applied onto skin surface and onto skin along the periphery of a stoma.

Use of cyanoacrylate adhesives for providing a protective barrier film

Alkyl cyanoacrylate compositions comprising at least one alkyl cyanoacrylate, a biocompatible plasticizer (preferably dioctyl phthalate), and SO.sub.2 as an artionic polymerization inhibitor are provided. These compositions are suitable for topical application to human skin.

A cyanoacrylate adhesive is applied onto surface skin areas prone to ulceration so as to inhibit formation of surface skin ulcers.

A liquid applicator bottle for holding and applying liquids, such as fabric paint, to surfaces is formed of a resiliently deformable hollow body. The bottle has a base at one end and sloped shoulders at the other end. The shoulders are angled toward each other to form a neck having an opening. A nozzle unit with a substantially cylindrical stem, sharply tapered to a flange, and having a passage therethrough, is mounted in the opening of the neck. The stem extends axially and outwardly from the flange, which is retained within the neck. A cap is removably mountable on the neck, in a covering relationship to the nozzle unit.

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Littleton, CO, United States of America

Patrick J Tighe