Abbott Laboratories Corporation

Patrick J Macdonald

Qiaoqiao Ruan

Sergey Y Tetin

Mark R Pope

Xiaoxing Qiu

John C Prostko

Zhen Lin

M Felicia Bogdan

Kerry M Swift

Richard Haack

Brenda Calfin

The disclosure provides methods of analyzing an analyte of interest in a biological sample using fluorescent agents and macroconjugates which comprise a core containing a cross-linked polymer or protein, tags, specific binding members or fragments thereof, and optionally carrier proteins. Also provided are methods of analyzing two or more analytes of interest in a biological sample in a single assay using microparticles and detection conjugates comprising different fluorophore labels, acquiring transmitted light and fluorescent images of the microparticles, and using a customized image analysis process to analyze the acquired images.

Direct detection of single molecules on microparticles

Growing community of inventors

Abbott Park, IL, United States of America

Patrick J Macdonald