Carbylan Therapeutics, Inc.

Patrick J Hillas

David M Gravett

Robert C Spiro

George Y Daniloff

Pingren He

The present application provides sterile hyaluronic polymer compositions than are useful, e.g., as medical devices, biomedical adhesives, and sealants. Generally, provided are sterile dry compositions comprising a thiol-derivatized hyaluronic acid and one or more stabilizing excipients. Also provided are related kits and methods. The compositions described herein are particularly robust to sterilizing irradiation, and substantially maintain both their molecular weight and gelation parameters such as gelation time after sterilization, such that such sterile compositions are capable of hydrogel formation.

Growing community of inventors

San Francisco, CA, United States of America

Patrick J Hillas