Paragon Bioteck, Inc.

Ocusoft, Inc.

Opus Life Sciences, LLC

Patrick H Witham

Sailaja Machiraju

Daniel Banov

Nat Adkins, Jr

Lauren Mackensie-Clark Bluett

August Bassani

Nat G Adkins, Jr

William Stringer

Compositions comprising a fluorescein component and benoxinate component and the corresponding uses of these compositions are described herein. These compositions have improved storage life and the fluorescein component and/or benoxinate component minimally degrade after 12 to 18 months of storage.

Fluorescein and benoxinate compositions

The invention is directed to methods and compositions of stabilizing phenylephrine formations. The composition has good time-dependent stability at low temperature and has no change in its outward appearance even after having been stored at least 6 months.

Methods and compositions of stable phenylephrine formulations

Fluorescein formulations and kits

Embodiments of the invention include a heated eyelid cleansing apparatus, a method of manufacturing a heated eyelid cleansing apparatus, a kit for providing treatment to the eyelids, and a method for cleansing an eyelid with a heated eyelid cleansing composition. The apparatus comprises an eyelid cleansing composition, a fabric pad impregnated with the eyelid cleansing composition, and a heating element. The heating element may be encased within the fabric pad or it may be external to the fabric pad.

Heated eyelid cleanser

An eyelid scrub composition comprising polyhexamethylene biguanide (PHMB), 1,2-hexanediol, 1,2-octanediol, and a pH stabilizing surfactant solution present in an amount effective to control the pH level of the composition between 5.5 and 7.5. The composition can further comprise moisturizers and foam stabilizers. The composition can be combined with a fabric pad for use as an eyelid scrub, where the fabric pad is pre-moistened with the composition and packaged for use. The composition may be applied to the eyelid scrub and rubbed to induce foaming. The composition is produced by preparing a modified Ringer's solution and adding 1,2-hexanediol, 1,2-octanediol, and an effective amount of one or more pH stabilizing surfactants. The mixture is then heated and allowed to cool before polyhexamethylene biguanide is added.

Eyelid scrub composition

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Eugene, OR, United States of America

Patrick H Witham