Morningside Venture Investments Limited

Chrono Therapeutics Inc.

Qmark Medical Inc.

Patrick H Ruane

Gary Stacey

Charles Frazer Kilby

Jennifer Darmour

Alexander David Norman

Alan Joel Levy

Congyi Huang

Timothy Charles Frearson

Zita S Netzel

David Evans Roth

Ling-Kang Tong

Kevin W Gelston

Jenny E Hapgood

Ronald A Overbeck

Sameer Sharma

Jackie Joe Hancock

Anubhav Arora

Described herein are drug and other active agent transdermal delivery systems and devices to deliver active agents to skin or mucosa of a subject, and methods of delivering such active agents. In particular, systems, methods, and devices are described that control the concentration and timing of active agent delivery. Such systems or devices may include a transdermal membrane and a temperature control element for heating and/or cooling a portion of the transdermal delivery system to provide pulsatile active agent delivery through the transdermal membrane.

Thermally regulated transdermal drug delivery system

A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.

Drug delivery methods and systems

An injectable medical composition includes an acrylate and a solvent. The composition has a first viscosity at temperatures below body temperature and a second viscosity at body temperature. The first viscosity is lower than the second viscosity.

Hydrogel composition for mucosal lifting procedures within lumenal anatomical structures

Growing community of inventors

Dublin, CA, United States of America

Patrick H Ruane