Becton Dickinson and Company Limited

Becton Dickinson France

Patrick G Carre

Robert B Odell

Claude Imbert

Frédéric Perot

Bruno Baney

James C Kropatsch

Mario De Aguero Servin

Jorge J Campos

Donald J Porfano

Mark A German

Patrick Dupuis

Colin May

Jean M Jouet

Donald L Porfano

Jorge Campos

Medical devices such as medical containers can be formed of glass and annealed which produces a clean device having a low bio-burden, or formed by plastic molding which produces a clean device. The clean devices are immediately transferred to a controlled environment such as a clean room or localized area to avoid the need to maintain cleanliness levels in an entire room. Syringe tip closures can be introduced into the housing assembly, where syringe barrels and tip closures are cleaned with filtered ionized air and the tip closures are coupled to the barrels. The syringe barrels can be filled with a substance and a closure member attached. While still in the housing assembly the syringe barrels can be formed into an array and placed in a clean outer container, which is then closed and sealed.

Method and apparatus for manufacturing, filling and packaging medical devices and medical containers

Clean syringe barrels from forming device immediately transferred to a controlled environment to maintain a clean work area. The work area can be a clean room or localized area to avoid the need to maintain cleanliness levels in an entire room. A localized area uses a housing assembly having a HEPA filter coupled to an air inlet to filter the air entering the housing. An air blower is coupled to the air inlet to feed filtered air into the housing assembly and to maintain a positive air pressure in the housing assembly to prevent unfiltered outside air from entering. Syringe tip closures can be introduced into the housing assembly, where syringe barrels and tip closures are cleaned with filtered ionized air and the tip closures are coupled to the barrels. A thin coating of lubricant is applied to the inner surfaces of the syringe barrels. The syringe barrels or medical container can be filled with a substance and a closure member is attached. While still in the housing assembly the syringe barrels can be formed into an array and placed in a clean outer container. The outer container is then closed and sealed. The outer container and syringe barrels can be sterilized with heat, radiation or by exposure to a sterilizing gas.

Glass medical devices such as medical containers are manufactured and annealed by heating in an oven which produces a clean device having a low bio-burden. Plastic medical devices and medical containers are formed by plastic molding devices which produce a clean device. The clean devices are immediately transferred to a controlled environment to maintain a clean work area. A localized area uses a housing assembly having a HEPA filter coupled to an air inlet to filter the air entering the housing. An air blower is coupled to the air inlet to feed filtered air into the housing assembly and to maintain a positive air pressure in the housing assembly to prevent unfiltered outside air from entering. Syringe tip closures can be introduced into the housing assembly, where syringe barrels and tip closures are cleaned with filtered ionized air and the tip closures are coupled to the barrels. A thin coating of lubricant is applied to the inner surfaces of the syringe barrels. The syringe barrels or medical container can be filled with a substance and a closure member is attached. While still in the housing assembly the syringe barrels can be formed into an array and placed in a clean outer container. The outer container is then closed and sealed. The outer container and syringe barrels can be sterilized with heat, radiation or by exposure to a sterilizing gas. The syringe barrels may be prefillable glass or plastic syringe barrels.

Needle shield

A syringe assembly includes a barrel having an open proximal end, a chamber for retaining fluid and a tip portion extending from a distal end of the barrel having a passageway therethrough communicating with the chamber. A needle cannula having a distal end extends outwardly from the tip portion and includes a lumen in fluid communication with the passageway. A needle shield assembly includes a resilient needle sheath having an open proximal end, a closed distal end, a sidewall defining a receptacle therein and an annular flange extending radially outwardly from the proximal end of the needle sheath. The needle sheath is positioned within an elongate rigid shield having an open proximal end, a distal end and a sidewall therebetween. Structure for holding the sheath within the shield includes a flange-receiving aperture in the needle shield sidewall adjacent to the open proximal end. The aperture includes a ledge on its proximal side for engaging the proximal side of the flange for holding the sheath in the shield. Structure is also provided for deflecting the annular flange causing more of the annular flange to project into the flange-receiving aperture than if the structure were not included. The needle shield assembly is positioned with the distal end of the cannula engaging the cannula sealing distal end of the sheath and the proximal end of the sheath removably engages the tip portion of the barrel to hold the shield assembly on the barrel while simutaneously sealing the lumen of the cannula.

Syringe assembly

Growing community of inventors

La Buisse, France

Patrick G Carre