Abbott Laboratories Corporation

Baxter International Inc.

Patrick F Jonas

Charles A Flentge

Donald D Johnson

Cynthia M Molina

Paul J Brynes

David Eugene Pereira

Susan L Trimbo

Francis Ros&eacute;

Bruce Rowe

Xavier Leverve

Synthetic enantiomeric esters are employed as energy substrates for parenteral or enteral nutritional formulations. The substrates are provided in substantially monoisomeric or anomeric forms readily utilized in patient metabolism.

Enantiomerically-enhanced nutritional energy substrates

A fluorescence polarization immunoassay (FPIA) for detecting the presence of one or more amphetamine-class analytes in a test sample is provided. The immunoassay uses competition between the analyte and a fluorescently labeled tracer for the binding site on an antibody specific for phenethylamine derivatives. The concentration of amphetamine-class analyte in the sample determines the amount of tracer that binds to the antibody. The amount of tracer-antibody complex formed can be quantitatively measured and is inversely proportional to the quantity of analyte in the test sample. The invention relates to tracers, to immunogens used to elicit antibodies for use as assay reagents, and to assay kits incorporating these tracers and assay reagents.

Reagents, methods and kits for an amphetamine-class fluorescence

A fluorescence polarization immunoassay (FPIA) for detecting the presence of one or more amphetamine-class analytes in a test sample is provided. The immunoassay uses competition between the analyte and a fluorescently labeled tracer for the binding site on an antibody specific for phenethylamine derivatives. The concentration of amphetamine-class analyte in the sample determines the amount of tracer that binds to the antibody. The amount of tracer/antibody complex formed can be quantitatively measured and is inversely proportional to the quantity of analyte in the test sample. The invention relates to tracers, to immunogens used to elicit antibodies for use as assay reagents, and to assay kits incorporating these tracers and assay reagents.

Reagents for an amphetamine-class fluorescence polarization immunoassay

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Waukegan, IL, United States of America

Patrick F Jonas