The University of Newcastle Upon Tyne

Imperial Innovations Limited

Patrick Degenaar

Donal Bradley

Andrew Jackson

Stuart Baker

Hubin Zhao

Fahimeh Dehkhoda

Ahmed Soltan

Anthony O'Neill

Mark Cunningham

Dehong Huo

Zi Jie Choong

Anthony O′Neill

Lichun Chen

A method of cutting (e.g. micro-milling) brittle materials where a protective ductile layer is present on the brittle material during the cutting step. The method offers an improved edge quality of the machined profile relative to previous cutting (e.g. micro-milling) techniques. A machined product obtained by or obtainable by this method is disclosed.

Method of machining brittle materials

An optogenetic system and method for preventing or halting seizures. The system and method use a sensor for monitoring the activity of a neural network containing a group of target neurons, and generating an input signal indicative of said activity, the target neurons being excitatory neurons. Excitatory stimulation is delivered in the form of an optical signal by an optical stimulator to the target neurons, the optical signal being determined based on the input signal, to reduce the overall activity of the target neurons.

Optogenetic system and method

An optrode arrangement for delivering optical stimulation to target tissue in a patient, the optrode arrangement comprising an implantable optrode comprising at least one electrically powered light emitter and an electrical circuit and control lines for controlling the light emitter, whereby an associated controller has two modes of operation: a stimulation mode in which it is configured to control the light emitter to deliver optical stimulation to the target tissue and a diagnostic mode in which it is configured to determine a condition of the light emitter and/or the optrode.

Implantable optrode with a controller configured for operation in a stimulation mode and in a diagnostic mode

A temperature sensor comprising a light emitter, an electrical circuit for applying a reverse bias voltage across the light emitter and for measuring a reverse current, and means for calculating a temperature from the measured reverse current.

Temperature sensor

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Tyne and Wear, United Kingdom

Patrick Degenaar