Adir Et Compagnie

Les Laboratoires Servier

Université De Caen

Patrick Dallemagne

Sylvain Rault

Pierre Renard

Pierre Lestage

Bruno Pfeiffer

Marie-C&eacute;cile Lebrun

Olivier Renault

Michel Boulouard

Jean Guillon

Beatrice Guardiola

Michelle Devissaguet

Max Robba

Christophe Rochais

Cedric Lecoutey

Thomas Freret

Cédric Lecoutey

Compounds are provided according to Formula (I) as well as their enantiomers and their racemics, their acid salts, their hydrates or their solvation products. Among a large number of possible meanings, X represents a halogen, Y an oxygen atom; all of the coefficients m, n, r and s have the value 1, R represents an ethyl and R' a cycloalkyl. The invention also includes Methods of preparing the above compounds and the pharmaceutical compositions containing them also are provided.

Acetylcholinesterase inhibitors and promnesiant serotonin 5-HT4 receptor agonists, their methods of preparation and the pharmaceutical compositions containing the same

1-aza-2-alky-6-aryl-cycloalkanes

1-aza-2-alkyl-6-aryl-cycloalkane compounds

The invention relates to compounds of general formula I: ##STR1## in which: R.sub.1 represents a radical of general formula (Z.sub.0), (Z.sub.1), (Z.sub.2), (Z.sub.3) or (Z.sub.4) ##STR2## R.sub.2 represents a methylene radical, a hydroxymethylene radical, a carbonyl radical or a radical of general formula (Y.sub.1), (Y.sub.2), (Y.sub.3) or (Y.sub.4): ##STR3## or, with R.sub.12 and the nitrogen atom to which they are attached, forms a radical of general formula (W): ##STR4## R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10, R.sub.11, R.sub.12 and n being as defined in the description, medicinal products containing the same and a method-of-treating metabolic ailments therewith.

Pyrrolo [1,2-a] thieno [3,2-f] (1,4) diazepines

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Saint Georges d'Aunay, France

Patrick Dallemagne