University of Rochester

University of Nebraska

Temple University

Patrick D Olson

Wayne Everett Childers

Paul M Dunman

Wayne Childers

Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection.

Small molecule RNase inhibitors and methods of use

Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease.

Growing community of inventors

St. Louis, MO, United States of America

Patrick D Olson