Institut National De La Sante Et De La Recherche Medicale

Universitãt Stuttgart

Armines

Centre National De La Recherche Scientifique

Université D'evry-Val-D'essonne

Association Pour La Recherche Et Le Developpement De Methodes Et Processus Industriels “Armines”

Inserm

Patrick Curmi

Fedor Jelezko

Jean-Paul Boudou

David Pastre

Alain Thorel

Mirela Boca

Mohamed Sennour

Michel Cailleret

A method for detecting an interaction between one or more protein bait and one or more candidate prey in a eukaryotic cell, comprising the steps of: a) providing an eukaryotic cell expressing (i) one or more protein bait, and (ii) one or more candidate prey, wherein said protein bait comprises a bait moiety and a polymerized-tubulin binding moiety. b) determining the occurence of an interaction between said one or more protein bait and said one or more candidate prey in the eukaryotic cell, wherein said protein bait is bound to polymerized tubulin in the eukaryotic cell, thereby localizing said one or more candidate prey along said polymerized tubulin, thereby detecting said interaction.

Methods and tools for detecting interactions in eukaryotic cells using microtubule structures and dynamics

A method for manufacturing cubic diamond nanocrystals () comprising the following successive steps: (a) providing crystalline diamond powder where the maximum particle size of the powder is equal or more than 2 um and equal or less than 1 mm; (b) milling said crystalline micron diamond powder using nitrogen jet milling micronization so as to manufacture a fine powder; (c) nanomilling the fine powder of step b) using a planetary tungsten carbide ball mill; (d) acid treating the nanomilled powder of step c); (e) extracting the cubic diamond nanocrystals () by centrifugation. Advantageously round-shaped cubic diamond nanocrystals are manufactured.

Method for manufacturing cubic diamond nanocrystals

Method to produce diamonds containing Nitrogen-Vacancy centers from diamonds grown by a high pressure and high temperature process and containing isolated substitutional nitrogen, comprising: &#x2014;Irradiating () said diamonds by an electron beam such that the irradiation dose is comprised between 10and 10electrons per square centimeter; &#x2014;annealing () the irradiated diamonds in vacuum or in a inert atmosphere at a temperature above 700&#xb0; C. and for at least 1 hour; characterized in that said electron beam has an acceleration energy above 7 MeV.

Method to produce light-emitting nano-particles of diamond

Method to produce diamonds containing Nitrogen-Vacancy centers from diamonds grown by a high pressure and high temperature process and containing isolated substitutional nitrogen, comprising: &#x2014;Irradiating (12) said diamonds by an electron beam such that the irradiation dose is comprised between 10and 10electrons per square centimeter; &#x2014;annealing (14) the irradiated diamonds in vacuum or in a inert atmosphere at a temperature above 700&#xb0; C. and for at least 1 hour; characterized in that said electron beam has an acceleration energy above 7 MeV.

Growing community of inventors

Evry, France

Patrick Curmi