Commissariat a L'energie Atomique

Biomerieux Sa

Commissariat a L'energie Atomique Et Aux Energies Alternatives

Etat Francais Represente Par Le Delegue General Pour L'armement

Commissariat À L'énergie Atomique Et Aux Énergies Alternatives

Patrick Chaton

Françoise Vinet

Ludovic Poupinet

Stephane Getin

Jean Dijon

Patrick Pouteau

Serge Gidon

Sergio Nicoletti

Bérangère Hyot

Thierry Leroux

Etienne Quesnel

Philippe Grosse

Gilles Grand

Bernard Andre

Stéphane Getin

Michel Ida

Pierre Barritault

Pierre Desre

Frédéric Ginot

François Perraut

Pascal Royer

Nathalie Picollet-D'Hahan

Armelle Novelli Rousseau

Jean-Louis Bijeon

Pierre Michel Adam

Jerome Petit

Jean-Baptiste Trebbia

Jérôme Petit

Frédérique Mittler

Device for detecting a gas having an excitation device for exciting the gas by an electromagnetic wave having a wavelength corresponding approximately to that of the gas; and a detection device for detecting the excitation of the gas, the detection device having a waveguide connected to the excitation device, a part of which forms a movable element designed to be in contact with the gas and capable of being set into vibration by the impact of the excited gas molecules; and a measurement sensor, for measuring the vibration of the element, the measurement sensor and the element forming the detection device.

Gas detection device

The invention relates to the field of optical information recording. In order to prevent abusive or fraudulent use of storage media, the invention provides a process for intentional degradation of information by application of a laser power below the normal power for reading information recorded in super-resolution on the media. This process relies on the surprising observation that a laser power below the super-resolution read power produces an irreversible degradation of the information recorded. This observation has been made with regard to media composed of a three-layer structure comprising an InSb or GaSb layer between two ZnS/SiOlayers. Application for protecting sensitive data.

Process for intentional deterioration of the contents of an optical recording medium

The invention concerns a device for enhancing fluorescence comprising a support () carrying fluorescence enhancement means (), the fluorescence enhancement means offering a reception surface for chemical or biological elements intended to be read by detection of a fluorescence signal emitted by a fluorophore, associated with the chemical or biological elements, under the effect of an excitation light beam. The fluorescence enhancement means () is made up of a thin, transparent, dielectric layer or a stack of thin, transparent, dielectric layers (to) ensuring a mirror function for the fluorescence signal and excitation light beam, the material of the thin layer or of each thin layer of the stack being chosen from among the following materials: TiO, TaO, HfO, ZrO, MgO, SiO, SiN, MgFand YF. The fluorescence enhancement device may be used for a biological or chemical optic sensor.

Device for enhancing broad band fluorescence with low loss and biological or chemical optic sensor using the same

A surface plasmon microsensor or a nanosensor for chemical or biological species including pads distributed on the surface of a support, the pads including an electrically conductive material and being capable of immobilizing the chemical or biological species. The pads have a dimension less than 1 &#x3bc;m.

Microsensors and nanosensors for chemical and biological species with surface plasmons

A method for controlling directly and in real time positioning of a biological element on a zone of a support, in which the biological element is labeled with a tracer that emits a light radiation and the zone of the support is located in a layer of a material capable of trapping the light radiation. The biological element is positioned on the zone of the support. The intensity of the light radiation trapped in the layer is measured. The positioning of the biological element is determined by comparing the intensity thus measured with at least one reference value. The above operations can be carried out successively or simultaneously. A device can apply the method to the positioning of one or more biological elements on one or more zones of a support.

Method and device for controlling the positioning of a biological element on a support

A device for measuring the dimensional or structural characteristics of an object. A detector forms an optical Fourier transform image of an elemental surface of the object in an image focal plane. A processor produces data relating to at least one dimensional and/or structural characteristic of the object from the information provided by the detector.

Use of optical fourier transform for dimensional control in microelectronics

A method and a device, using a system of plural cavity resonators, enabling to measure the light absorption or diffusion of biological samples. A measurement of low absorption or diffusion can be achieved and for example be applied for measuring the hybridization of DNA strands.

Method and device for measuring the absorption or light diffusion of biological elements

A process for characterizing, quantifying or mapping a nucleic acid or a nitrogenous base fixed on a support by using a photothermal (mirage effect) method. An improved process for manufacturing a nucleic acid biochip on which at least one nucleic acid synthesized in situ is fixed. A device for implementing these processes.

Method and device for analyzing nucleic acids immobilized on a support

A device and process for the amplification of fluorescence emitted by an areal sample. The device includes a support transmitting all or part of a fluorescence signal and configured to support the areal sample and a thin layer interposed between the support and the areal sample. The thin layer has a refractive index greater than the refractive index of the support and than the refractive index of a medium flooding the areal sample during a fluorescence measurement. The thickness of the thin layer is chosen so that the thin layer transmits all or part of the fluorescence signal which is measured after passing through the support.

Enhancing surface-generated fluorescence signal emitted by a sample

The present invention relates to a method for detection of a molecular recognition reaction without labelling and a device for using this method. This invention concerns the general field of detection and analysis of molecular recognition between a first and a second molecule, for example a biological molecule. The method of the present invention consists of the detection of the molecular recognition by a photothermal method.

Method and device for detecting a molecular recognition reaction

Light absorbing coating with high absorption capacity

The invention relates to a low-pass optical filtering device for the UV band, comprising:

Low-pass filter for the UV band of the electromagnetic spectrum

A high reflectivity, broad band mirror for a high flux laser and a process for producing such a mirror. The mirror includes a substrate on which is formed a metallic layer such as aluminum. A stack of layers are formed on the metallic layer. The stack includes alternating layers of two materials with the refractive index of one material being higher than that of the other. A surface layer of a third material is placed on the stack. The surface layer has a refractive index which varies in accordance with the continuous periodic profile. The mirror is formed by depositing the metallic layer on a substrate and forming the stack by an ion beam sputtering method.

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Theys, France

Patrick Chaton