Biomerieux, Inc.

Biomerieux Sa

Snpe Materiaux Energetiques

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Commissariat a L'energie Atomique

Bio{acute Over (m)}erieux

Patrick Broyer

Bruno Colin

Denis Roller

Hervé Rostaing

Jérôme Blaze

Philippe L Cleuziat

Frédéric Pinston

Michel Guy

Nadine Perrot

Pradip Patel

Nicole Pamme

Bernard F Mandrand

Charles H Rogers

Cyril Delattre

Laurent Drazek

Claude Mabilat

Christian Jeandey

Jean-Claude Raymond

Hermanus Johannes Maria Kreuwel

Cécile Paris

Agnès Dupont-Filliard

Emiel Gerebern Maria Verwimp

Frédéric Foucault

Marie-Hélène Charles

Francis Garnier

Bernard Jean-Marie Limon

C&eacute;cile Paris

Pierre Imbaud

Lyse Santoro

Laurent Veron

Carole Vachon

Emiliano Maione

Sandra Incardona

Guillaume Durin

Massimo Galdiero

Jean-Marie Baumlin

Emilie Bisceglia

Agnès Dupont Filliard

Agnes Dupontfilliard

Thierry Kollaroczy

Magaly Ponsard-Fillette

Sandrine Gicquel

Matthieu Goujard

Agnès Dupontfilliard

The invention provides an analysis plate () including at least one analysis zone for receiving a sample to be analyzed by mass spectrometry using the MALDI-TOF technique, the plate being of the type having at least one test face () with at least one analysis zone defined thereon and of the type in which the plate includes a support () that is plane, the plate being characterized in that the support () comprises at least one sheet () of paper material comprising cellulose fibers, and in that the analysis plate () includes at least one ply () of metal material.

MALDI-TOF analysis plate with paper support and use thereof

An extraction system includes a support bar including a sample well, a reagent well, at least one washing well, and at least one protection and retention housing; a pipetting element removably mounted on the support bar and extending at least partially into the at least one protection and retention housing; and a filtering and transfer device configured to capture and accumulate microorganisms contained in the sample and transfer the captured and accumulated microorganisms, the filtering and transfer device being removably mounted on the support bar and extending at least partially into the at least one protection and retention housing. The filtering and transfer device includes a hollow body having an elongated shape and including a proximal end portion and a distal end portion; and a filtering element fixed to the distal end portion of the hollow body.

Extraction system and method for extracting microorganisms contained in a sample

The invention relates to a device for obtaining biological material and/or biological information from a sample with a heterogeneous matrix, to the uses of said device, to methods implementing said device, and to kits for obtaining biological material and/or biological information from a sample with a heterogeneous matrix, comprising the different constituents of said device.

Device for obtaining biological material and/or biological information from a sample with a heterogeneous matrix

A method of treating a biological sample, preferably a sample of blood or bodily fluids likely to contain one or more species of interest, and including a step of decomplexification by acoustophoresis (as well as associated systems, devices, substrates and connection devices).

Method and devices for treating biological samples

A method for treating a biological sample, preferably a food sample which may contain one or more species of interest, including a step of decomplexification by acoustophoresis.

Method for treating biological samples, especially food samples

A device for preparing biological samples including a fixed support of which the base extends in a first plane, a filtration block that can be removable, the filtration block including a collecting tank that itself includes a filtering device extending in a second plane and dividing the collecting tank into a collection area and a suction area, the suction area being designed to be connected to a suction device, the second plane of the filtering device being inclined relative to the plane of the base of the fixed support.

Device for preparing biological samples

The present invention relates to a disposable device () for amplifying at least one target nucleic acid present in a liquid and biological sample of interest, which consists of a solid body (), at least one fluid channel () connecting an inlet (), via which all or part of the sample of interest can be drawn up and/or discharged, and an outlet (), which is itself connected to a means for the drawing up/discharging of the said sample of interest, the fluid channel () further comprising from the inlet () to the outlet (): The invention also proposes an amplification method using such a device. The said invention has a preferred application in the field of medical diagnosis.

Simplified device for nucleic acid amplification and method for using same

The invention relates to a device for preparing and/or treating a biological sample including an assembly () of storage chambers () and/or reaction chambers intended for receiving a fluid and means arranged to move an amount of fluid from and/or to at least one of the chambers () of the assembly () of chambers (), the chambers () being separated by walls () so as to form an assembly of adjacent chambers () aligned in a given direction. The means arranged to move an amount of fluid include a needle () connected to a transfer space (), means () arranged to enable the suction of a liquid towards a chamber () from a transfer space () via a needle or delivery from the transfer space () to a chamber (), and driving means () arranged to translate the needle () and the assembly () of chambers relative to one another in the chamber () alignment direction, and in that two adjacent chambers () are separated by a wall including a sealing membrane () or septum capable of being pierced by the needle () and of then recovering the seal thereof once the needle is removed. The invention also relates to a method for manufacturing such a device.

Device for preparing and/or treating a biological sample

The present invention relates to, among other things, a device for collecting airborne microorganisms, said device having:

Automated system for the lysis of microorganisms present in a sample, for extraction and for purification of the nucleic acids of said microorganisms for purposes of analysis

The invention relates to a microsystem and a method for fabricating a microsystem. The pyrotechnic microsystem (') comprises a substrate having at least two separate electrical initiation zones, each of which provides separate electrical initiation of a pyrotechnic material deposited on the substrate. This microsystem (&#x2032;) is characterized in that the same pyrotechnic material deposit () covers both initiation zones, said deposit () produced on the substrate having a thickness sufficiently small for the initiation of the pyrotechnic material in the initiation zone to remain localized and not propagate to the other initiation zone, but sufficient to generate a specific gas quantity.

Pyrotechnic microsystem and method for fabricating a microsystem

A reaction card () having a body, a front surface () and a rear surface () defined by an edge (), at least one inlet (and/or) and at least one outlet (and/or), connected by a network of channels () constituting at least one reaction path for at least one fluid which is directed via valves (toand/or); each valve includes a flexible film () which can be deformed to allow fluid passage, the film being fixed on the card's rear surface at a peripheral indentation of an assembly of channels associated with the valve; the card includes channels flush with at least one of its surfaces, the channels being of two different cross-sections, a small cross-section serving as a reaction compartment; each front or rear surface is delimited by at least one film (and/or).

Reaction card and use of same

The invention relates to a device for the electrical initiation of at least one pyrotechnic microcharge (), this device being characterized in that it comprises a support element having at least one conductive finger () connected to a first terminal of a central control unit (), a second terminal of said central control unit () being intended to be electrically connected to an electrically conductive support for the pyrotechnic microcharge (). The invention also relates to a microactuator () and a microsystem () that use such an initiation device.

Device for the electrical initiation of a pyrotechnic microcharge, and microsystem using such a device

Method for the wet dynamic separation of a suspension in liquid phase, comprising microparticles comprising a magnetic material and a liquid medium in which said microparticles are in suspension, in which method:

Method, device and apparatus for the wet separation of magnetic microparticles

The invention relates to an electrically-opened micro fluid-valve. The inventive valve comprises: at least one planar support (); at least one afferent microchannel (); at least one efferent microchannel (), said microchannels being arranged in the support (); such that at least one of the ends (and) thereof touch the inner face () of the support close to one another; at least one deposit () of a heat-sensitive material which is disposed on the inner face () of the support (); and at least one heating means (). According to the invention, the aforementioned deposit () of heat-sensitive material at least partially seals the space separating the ends (and) of the microchannels (and), thereby preventing same from intercommunicating. When the temperature of the above-mentioned heating means () is raised, the structure of the heat-sensitive material is altered, thereby at least partially opening the ends of the microchannels an the space therebetween, in order to enable communication between said microchannels and to restore the flow of the fluid.

Electrically opened micro fluid valve

The invention concerns the technical field of micro-actuators used for mechanical, chemical, electrical or thermal functions in microsystems, for microelectronic applications such as chips, or biomedical functions such as microfluidics integrating cards. The invention concerns a micro-actuator comprising a so-called main chamber, made in a solid support and containing a so-called main pyrotechnic charge, the main chamber being sealed and delimited by solid support walls and by a deformable membrane, such that the gases emitted by the combustion of the main pyrotechnic charge, enable the volume of the chamber to be increased by deforming the membrane while maintaining intact the solid walls of the main chamber. The invention is characterized in that it comprises means for evacuating the gases from the main chamber.

Double-effect pyrotechnic microactuator for microsystem and microsystem using same

Growing community of inventors

Saint Cassien, France

Patrick Broyer