Micromidas, Inc.

The Dow Chemical Company

Dow Global Technolgoies LLC

Central Michigan University

Patrick B Smith

Dennis A Hucul

Makoto Nathanael Masuno

Ryan L Smith

Katherine Brune

John Bissell

Dimitri A Hirsch-Weil

Edmund J Stark

Alex Benjamin Wood

Douglas Cannon

Robert K Prud'homme

Daniel Randolph Henton

David J Moll

David M Meunier

Bobby A Howell

Adina Dumitrascu

Cuiwei Zhang

John A Bissell

Scott A Baker

The present invention provides a sustained release composition having hyperbranched polymers that are polyesters that are biobased and biodegradable, and that have at least one active ingredient, which composition delivers the active ingredient over time. These active ingredients can be a wide variety of compounds so long as they can covalently bind to the polymer or be encapsulated in the polymer in a manner that is released at the point of delivery, usually by acid hydrolysis or enzymatic bond scission.

Sustained release composition using biobased biodegradable hyperbranched polyesters

The present disclosure provides methods to produce para-xylene, toluene, and other compounds from renewable sources (e.g., cellulose, hemicellulose, starch, sugar) and ethylene in the presence of a catalyst. For example, cellulose and/or hemicellulose may be converted into 2,5-dimethylfuran (DMF), which may be converted into para-xylene by cycloaddition of ethylene to DMF. Para-xylene can then be oxidized to form terephthalic acid.

Methods of producing para-xylene and terephthalic acid

The present disclosure provides methods to produce para-xylene, toluene, and other compounds from renewable sources (e.g., cellulose, hemicellulose) and ethylene in the presence of an acid, such as a Lewis acid. For example, cellulose and/or hemicellulose may be converted into 2,5-dimethylfuran (DMF) and 2-methylfuran, which may be converted into para-xylene and toluene, respectively. In particular, para-xylene can then be oxidized to form terephthalic acid.

Methods of producing para-xylene

A process for characterizing a sample comprising a population of linear macromolecules of interest () and a population of long chain branched macromolecules of interest (), the process including four steps. The first step is to provide a flow through separating medium () and a liquid eluant () in which the macromolecules of interest dissolve, the separating medium defining flow through channels (), the eluant flow rate and the average diameter of the channels being in a range so that the linear macromolecules of interest elute before the long chain branched macromolecules of interest () (). The second step is to introduce a sample into the liquid eluant. The third step is to flow the liquid eluant under pressure through the channels () of the separating medium (). The fourth step is to differentiate the linear macromolecules of interest () from the long chain branched macromolecules of interest () based on their successive elution volumes established in the third step such as by determining the refractive index of the successive elution volumes or by subjecting the successive elution volumes to size exclusion chromatography.

Molecular topological fractionation of macromolecules

A method and apparatus for determining the effects of pressure and/or dissoved gas on the molecular dynamics in solids, such as glassy polymers, or gases sorbed by the solids, involves the use of nuclear magnetic resonance (NMR) spectroscopy wherein a pressure resistant sample cell is combined with an NMR probe which in turn is subjected to a magnetic field, a diffusion gas being injected into the sample cell under varying pressure with resultant NMR spectra being collected and correlated.

Method and apparatus for determining molecular dynamics of materials

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Midland, MI, United States of America

Patrick B Smith