Harvard College

University of Washington

Patricia Silva Lima

Jon Clardy

E Peter Greenberg

Mohammad Seyedsayamdost

Josephine R Chandler

Breck Duerkop

Joshua Alan Blodgett

The present inventions are directed to a novel bactobolin analog bactobolin D. The present inventions also are directed to a method of producing a composition comprising at least one bactobolin analog using a bacteria strain comprising a bacterial cell comprising the biosynthetic locus of the bactobolin analog in(bta cluster) or a homolog structure (at least 95% sequence identity) thereof, and further isolation and purification of the bactobolin analog. For example, the bacterial strain can be a wild type bacterial strain such as astrain comprising a bta cluster (e.g.(e.g. E264, Bt4, and TXDOH) and(e.g. K96243, 1106a, and 1106b).

Bactobolin analog and synthesis method thereof

Growing community of inventors

Duque de Caxias, Brazil

Patricia Silva Lima