Northwestern University

Other

Massachusetts Institute of Technology

Patricia G Spear

Rebecca I Montgomery

Gary H Cohen

Roselyn J Eisenberg

John D Lambris

Robert D Rosenberg

Deepak Shukla

Wanda M Martinez

Claude Krummenacher

Maria Rosa Sarrias

Charles J Whitbeck

Robert J Geraghty

Morgyn S Warner

Disclosed herein are polysaccharide preparations enriched in 3-OST-3 modified heparan sulfate. Also disclosed are methods of treating herpes simplex viral type-1 infection using the pharmaceutical preparations of the invention.

Pharmaceutical preparations for the inhibition of herpes simplex virus 1 entry

The invention includes antiherpesviral peptides and method of generating the same.

Peptides for inhibition of herpes simplex virus entry

A cellular herpesvirus entry protein, or a mutant, a homolog, a derivative, a variant or a biologically active fragment thereof, suspended in a pharmaceutically active carrier in an amount effective to inhibit entry of an alphaherpesvirus into a cell, wherein the cellular herpesvirus entry protein is a member of the immunoglobulin superfamily, is provided and method of use thereof

Cellular proteins which mediate herpesvirus entry

The present invention provides isolated and purified polynucleotides that encode HVEM of mammalian origin, expression vectors containing those polynucleotides, host cells transformed with those expression vectors, a process of making HVEM using those polynucleotides and vectors, and isolated and purified HVEM.

Antibody to herpes virus entry receptor protein

Herpes virus entry receptor protein

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Chicago, IL, United States of America

Patricia G Spear