Commissariat a L'energie Atomique

Serono Genetics Institute S.a.

Patricia Claustre

Yves Fouillet

Raymond Charles

Nicolas Sarrut

Jean-Frederic Clerc

Claude Vauchier

Christine Peponnet

The invention concerns the performing, in continuous flow, of a biological, chemical or biochemical protocol on substances to be analysed, comprising several steps which consists in: in causing a mobile analysis support () comprising means () for receiving substances to be analysed and reagents to move past; implementing the steps of the protocol on the substances as the mobile analysis support () moves past.

Method and system for performing in continuous flow a biological, chemical or biochemical protocol

The invention relates to a device () for distribution of at least one liquid product, the device comprising at least one injection tube () supplied by a liquid product and being provided with an outlet orifice () capable of cooperating with an inlet orifice () of a reception tube () for reception of each liquid product. According to the invention, the outlet orifice () of each injection tube () and the inlet orifice () of the reception tube () open up into a sealed reservoir () full of an immiscible liquid (), the outlet orifice () of each injection tube () being at a spacing from the inlet orifice () of the reception tube () and able to be located close to the reception tube (), the device () also comprising means () for pressurizing the immiscible liquid ().

Liquid product distribution device and method

Devices and methods for carrying out a chemical or biochemical protocol are disclosed. In one embodiment, the chemical or biochemical protocol is performed by cycling at least one thermal transfer member between at least two temperatures while liquid samples on which the chemical or biochemical protocol is to be performed are continuously moving through at least one temperature regulated zone upon which the at least one thermal transfer member acts. In some embodiments, the device comprises a sample transport member that comprises liquid samples in sample receiving regions. The sample transport member moves the samples continuously through a temperature regulated zone which cycles between at least two temperatures while the liquid samples are moving through a temperature regulated zone on which at least one thermal transfer member acts. In some embodiments, the sample receiving regions comprise wells, hydrophillic films or hydrophillic filaments.

Method for carrying out a biochemical protocol in continuous flow in a microreactor

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Moirans, France

Patricia Claustre