Edwards Lifesciences Corporation

Medtronic Vascular, Inc.

Patrice Tremble

Crystal M Cunanan

Michael N Helmus

Kishore Udipi

Peiwen Cheng

Eugene Tedeschi

Wenda Carlyle

Tan Dinh

Diane Judd

Christine May Cabiling

Dianne Judd

The gradient coated stentof the present invention provides a coated stent having a continuous coatingdisposed on the stent elements. The continuous coatingincludes a first coating component and a second coating component. The concentration of the first coating component varies continuously over at least part of the thickness of the continuous coating. The concentration of the second coating component can also vary over at least part of the thickness of the continuous coating. In one embodiment, the concentration of the first coating component decreases in the direction from the stent element towards the outer edge of the continuous coatingand the concentration of the second coating component increases in the direction from the stent element towards the outer edge of the continuous coating

Gradient coated stent and method of fabrication

The invention provides methods for treating injuries to one or more internal structures of a subject by administering a drug delivery vehicle to an external surface of the injured structure. The drug delivery vehicle substantially adheres to the site of administration and provides for the release of a bioactive agent that reduces or prevents further injury to the internal structure by disease processes, such as hyperplasia.

Delivery systems for periadventitial delivery for treatment of restenosis and anastomotic intimal hyperplasia

A highly sensitive and specific method for the detection and quantification of lipids is provided. Specifically, methods for the simultaneous detection and quantification of phospholipids extracted from mammalian tissues is described. The analytical methods provided disclose a modified one-dimensional thin-layer chromatography technique specifically developed to rapidly and accurantely detect and quantify phospholipids from mammalian cardiac tissues.

Methods for quantitative and qualitative analyses of phospholipids using one-dimensional thin layer chromatography

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Santa Rosa, CA, United States of America

Patrice Tremble